Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 13/20 | 0.47 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.30 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1130652 | 0.88 | IGF1R (0.47) | IGF1RROCK1AR | |
| SCHEMBL1130931 | 0.87 | IGF1R (0.51) | IGF1RROCK1AR | |
| SCHEMBL1131107 | 0.84 | IGF1R (0.46) | IGF1RROCK1AR | |
| SCHEMBL1130395 | 0.83 | IGF1R (0.54) | IGF1RAR | |
| SCHEMBL1130958 | 0.83 | IGF1R (0.54) | IGF1R | |
| SCHEMBL1130662 | 0.83 | IGF1R (0.49) | IGF1RROCK1AR | |
| SCHEMBL1130034 | 0.82 | IGF1R (0.49) | IGF1RROCK1AR | |
| SCHEMBL1130711 | 0.82 | IGF1R (0.49) | IGF1RROCK1AR | |
| SCHEMBL1130513 | 0.81 | IGF1R (0.49) | IGF1RROCK1AR | |
| SCHEMBL1130519 | 0.80 | IGF1R (0.48) | IGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1773808-A2 | NOVEL CYCLIC UREA DERIVATIVES, PREPARATION THEREOF AND PHARMACEUTICAL USE THEREOF AS KINASE INHIBITORS | Aventis Pharma S.A. (FR) | 2007-04-18 | — | — | EP | disclosed |
| WO-2006010641-A2 | NOVEL CYCLIC UREA DERIVATIVES, PREPARATION THEREOF AND PHARMACEUTICAL USE THEREOF AS KINASE INHIBITORS | AVENTIS PHARMA S.A. (FR) | 2006-02-02 | — | — | WO | disclosed |