Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 7/20 | 0.57 |
| ▸ | GRM3 | Q14832 | 4/20 | 0.57 |
| ▸ | GRM6 | O15303 | 1/20 | 0.48 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5566850 | 1.00 | GRM2 (0.57) | GRM2GRM3GRM6GRM5 | |
| SCHEMBL5567611 | 1.00 | GRM2 (0.57) | GRM2GRM3GRM6GRM5 | |
| SCHEMBL4665515 | 1.00 | GRM2 (0.57) | GRM2GRM3GRM6GRM5 | |
| SCHEMBL4665462 | 1.00 | GRM2 (0.57) | GRM2GRM3GRM6GRM5 | |
| SCHEMBL5566895 | 0.85 | GRM2 (0.56) | GRM2GRM3GRM6GRM5 | |
| SCHEMBL8270206 | 0.85 | GRM2 (0.56) | GRM2GRM3GRM6GRM5 | |
| SCHEMBL4663596 | 0.85 | GRM2 (0.56) | GRM2GRM3GRM6GRM5 | |
| SCHEMBL5562908 | 0.85 | GRM2 (0.56) | GRM2GRM3GRM6GRM5 | |
| SCHEMBL4663693 | 0.85 | GRM2 (0.56) | GRM2GRM3GRM6GRM5 | |
| SCHEMBL5562659 | 0.84 | GRM2 (0.54) | GRM2GRM3GRM6GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1751099-A1 | CIS PYRROLIDINYL DERIVATIVES AND THEIR USES | Faust Pharmaceuticals (FR) | 2007-02-14 | — | — | EP | claimed |
| WO-2005118534-A1 | CIS PYRROLIDINYL DERIVATIVES AND THEIR USES | FAUST PHARMACEUTICALS (FR) | 2005-12-15 | — | — | WO | claimed |
| EP-1604977-A1 | CIS pyrrolidinyl derivatives and their uses | Faust Pharmaceuticals (FR) | 2005-12-14 | — | — | EP | claimed |
| EP-1751099-A1 | CIS PYRROLIDINYL DERIVATIVES AND THEIR USES | Faust Pharmaceuticals (FR) | 2007-02-14 | — | — | EP | disclosed |
| WO-2005118534-A1 | CIS PYRROLIDINYL DERIVATIVES AND THEIR USES | FAUST PHARMACEUTICALS (FR) | 2005-12-15 | — | — | WO | disclosed |
| EP-1604977-A1 | CIS pyrrolidinyl derivatives and their uses | Faust Pharmaceuticals (FR) | 2005-12-14 | — | — | EP | disclosed |