Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 20/20 | 0.77 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.53 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5205598 | 0.86 | DPP4 (0.97) | DPP4 | |
| SCHEMBL8267018 | 0.85 | DPP4 (1.00) | DPP4DPP8DPP9 | |
| Hydrochloric Acid SCHEMBL5204236 | 0.84 | DPP4 (0.97) | DPP4DPP8DPP9 | |
| Hydrochloric Acid SCHEMBL5206737 | 0.84 | DPP4 (0.97) | DPP4DPP8DPP9 | |
| SCHEMBL5567621 | 0.84 | DPP4 (0.77) | DPP4 | |
| Hydrochloric Acid SCHEMBL5206597 | 0.83 | DPP4 (0.97) | DPP4DPP8DPP9 | |
| SCHEMBL5567538 | 0.83 | DPP4 (0.76) | DPP4DPP8DPP9 | |
| SCHEMBL5564968 | 0.83 | DPP4 (0.76) | DPP4DPP8DPP9 | |
| Hydrochloric Acid SCHEMBL6172699 | 0.82 | DPP4 (0.95) | DPP4DPP8DPP9 | |
| SCHEMBL5568878 | 0.80 | DPP4 (0.71) | DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7268150-B2 | 2-cyano-4-fluoropyrrolidine derivative or its salt | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 2007-09-11 | — | — | US | claimed |
| US-20050176771-A1 | 2-Cyano-4-fluoropyrrolidine derivative or its salt | ASTELLAS PHARMA INC. (JP) | 2005-08-11 | — | — | US | claimed |
| EP-1541551-A1 | 2-CYANO-4-FLUOROPYRROLIDINE DERIVATIVE OR ITS SALT | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 2005-06-15 | — | — | EP | claimed |
| US-7268150-B2 | 2-cyano-4-fluoropyrrolidine derivative or its salt | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 2007-09-11 | — | — | US | disclosed |
| US-20050176771-A1 | 2-Cyano-4-fluoropyrrolidine derivative or its salt | ASTELLAS PHARMA INC. (JP) | 2005-08-11 | — | — | US | disclosed |
| EP-1541551-A1 | 2-CYANO-4-FLUOROPYRROLIDINE DERIVATIVE OR ITS SALT | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 2005-06-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050176771-A1 | 2-Cyano-4-fluoropyrrolidine derivative or its salt | DPP4, DPP7, DPP9 | DPP4 1/4885DPP8 4/4885DPP9 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.