Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CDC7 | O00311 | 1/20 | 0.44 |
| ▸ | CIT | O14578 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | PIM1 | P11309 | 1/20 | 0.44 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.44 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.44 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.44 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 6/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.44 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL4956569 | 0.91 | SCN10A (0.48) | SCN10ALMNAL3MBTL1CDC7CIT | |
| Trifluoroacetic Acid SCHEMBL29562481 | 0.85 | SCN10A (0.55) | SCN10APARP1NPY5RHCRTR1HCRTR2 | |
| SCHEMBL8273965 | 0.78 | SCN10A (0.55) | SCN10ACDC7CITCYP1A2PIM1 | |
| Trifluoroacetic Acid SCHEMBL1294019 | 0.78 | SCN10A (0.47) | SCN10APARP1NPY5RHCRTR1HCRTR2 | |
| SCHEMBL1836335 | 0.77 | SCN10A (0.62) | SCN10APARP1NPY5RPOLBRAB9A | |
| SCHEMBL1836345 | 0.77 | SCN10A (0.62) | SCN10APARP1NPY5RPOLBRAB9A | |
| Trifluoroacetic Acid SCHEMBL1293715 | 0.77 | SCN10A (0.46) | SCN10ACDC7PARP1NPY5RDGAT1 | |
| SCHEMBL1841241 | 0.75 | SCN10A (0.56) | SCN10ACDC7CITCYP1A2PIM1 | |
| SCHEMBL12053448 | 0.74 | SCN10A (0.67) | SCN10APARP1NPY5RRAB9AMAPT | |
| SCHEMBL12798656 | 0.73 | SCN10A (0.66) | SCN10ACDC7CITCYP1A2PIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1786806-A1 | DPP-IV INHIBITORS | Santhera Pharmaceuticals (Schweiz) AG (CH) | 2007-05-23 | — | — | EP | disclosed |
| WO-2005121131-A1 | DPP-IV INHIBITORS | SANTHERA PHARMACEUTICALS (SCHWEIZ) AG (CH) | 2005-12-22 | — | — | WO | disclosed |