Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 20/20 | 0.71 |
| ▸ | ITGA5 | P08648 | 20/20 | 0.71 |
| ▸ | ITGB3 | P05106 | 12/20 | 0.68 |
| ▸ | ITGAV | P06756 | 12/20 | 0.68 |
| ▸ | ITGB5 | P18084 | 8/20 | 0.65 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5560195 | 0.92 | ITGB1 (0.84) | ITGB1ITGA5ITGB3ITGAVITGB5 | |
| SCHEMBL14453405 | 0.92 | ITGB1 (0.84) | ITGB1ITGA5ITGB3ITGAVITGB5 | |
| SCHEMBL5568537 | 0.91 | ITGB1 (0.85) | ITGB1ITGA5ITGB3ITGAVITGB5 | |
| SCHEMBL5567573 | 0.87 | ITGB1 (0.69) | ITGB1ITGA5ITGB3ITGAVITGB5 | |
| SCHEMBL5569578 | 0.87 | ITGB1 (0.83) | ITGB1ITGA5ITGB3ITGAVITGB5 | |
| SCHEMBL5568652 | 0.86 | ITGB1 (0.67) | ITGB1ITGA5ITGB3ITGAVITGB5 | |
| SCHEMBL5567431 | 0.85 | ITGB1 (0.68) | ITGB1ITGA5ITGB3ITGAVITGB5 | |
| SCHEMBL5561233 | 0.85 | ITGB1 (0.83) | ITGB1ITGA5ITGB3ITGAVITGB5 | |
| SCHEMBL14453403 | 0.85 | ITGB1 (0.83) | ITGB1ITGA5ITGB3ITGAVITGB5 | |
| SCHEMBL14453401 | 0.85 | ITGB1 (0.79) | ITGB1ITGA5ITGB3ITGAVITGB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005090329-A9 | NEW COMPOUNDS FOR THE INHIBITION OF ANGIOGENESIS AND USE OF THEREOF | JERINI AG (DE) | 2007-02-01 | — | — | WO | claimed |
| WO-2005090329-A9 | NEW COMPOUNDS FOR THE INHIBITION OF ANGIOGENESIS AND USE OF THEREOF | JERINI AG (DE) | 2007-02-01 | — | — | WO | disclosed |