Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.73 |
| ▸ | PLK4 | O00444 | 9/20 | 0.42 |
| ▸ | AURKB | Q96GD4 | 6/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | FLT3 | P36888 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | SI | P14410 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.39 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 3/20 | 0.39 |
| ▸ | SNRNP200 | O75643 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14547228 | 0.90 | GSK3B (0.59) | GSK3BPLK4AURKBCYP2C19FLT3 | |
| SCHEMBL5568336 | 0.82 | GSK3B (0.49) | GSK3BPLK4AURKBCYP2C19FLT3 | |
| SCHEMBL14547133 | 0.82 | GSK3B (0.48) | GSK3BPLK4AURKBCYP2C19FLT3 | |
| SCHEMBL14547263 | 0.82 | GSK3B (0.48) | GSK3BPLK4AURKBCYP2C19FLT3 | |
| SCHEMBL14547269 | 0.81 | GSK3B (0.47) | GSK3BPLK4AURKBCYP2C19FLT3 | |
| SCHEMBL14547145 | 0.81 | GSK3B (0.47) | GSK3BPLK4AURKBCYP2C19FLT3 | |
| SCHEMBL14547305 | 0.81 | PLK4 (0.49) | GSK3BPLK4AURKBCYP2C19FLT3 | |
| SCHEMBL14547144 | 0.79 | GSK3B (0.46) | GSK3BPLK4AURKBCYP2C19FLT3 | |
| SCHEMBL14547275 | 0.79 | GSK3B (0.46) | GSK3BPLK4AURKBCYP2C19FLT3 | |
| SCHEMBL1975786 | 0.78 | PLK4 (0.49) | GSK3BPLK4AURKBCYP2C19FLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7205328-B2 | Aids viricide | IRM LLC (BM) | 2007-04-17 | — | — | US | disclosed |
| US-7205328-B2 | Aids viricide | IRM LLC (BM) | 2007-04-17 | — | — | US | disclosed |
| US-7205328-B2 | Aids viricide | IRM LLC (BM) | 2007-04-17 | — | — | US | disclosed |
| US-20040152755-A1 | Oxindoles with anti-HIV activity | IRM LLC, A DELAWARE LLC (BM) | 2004-08-05 | — | — | US | disclosed |
| WO-2004037247-A1 | OXINDOLES WITH ANTI-HIV ACTIVITY | IRM LLC (BM) | 2004-05-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040152755-A1 | Oxindoles with anti-HIV activity | IDO1, API5, NFATC1 | GSK3B 566/4885PLK4 1823/4885AURKB 1397/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.