⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2523637 | 0.77 | — | — | |
| SCHEMBL11090528 | 0.77 | — | — | |
| SCHEMBL5181994 | 0.77 | — | — | |
| SCHEMBL841668 | 0.73 | — | — | |
| SCHEMBL9739142 | 0.72 | — | — | |
| SCHEMBL5168246 | 0.72 | — | — | |
| SCHEMBL12924126 | 0.72 | — | — | |
| SCHEMBL11897400 | 0.70 | — | — | |
| SCHEMBL5702043 | 0.69 | MEN1 (0.30) | — | |
| SCHEMBL29656012 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070244154-A1 | Substituted Tricyclic Benzimidazoles | ALTANA PHARMA AG (DE) | 2007-10-18 | — | — | US | disclosed |
| EP-1758900-B1 | SUBSTITUTED TRICYCLIC BENZIMIDAZOLES | NYCOMED GMBH (DE) | 2007-10-03 | — | — | EP | disclosed |
| EP-1758900-A1 | SUBSTITUTED TRICYCLIC BENZIMIDAZOLES | Altana Pharma AG (DE) | 2007-03-07 | — | — | EP | disclosed |
| WO-2005121139-A1 | SUBSTITUTED TRICYCLIC BENZIMIDAZOLES | ALTANA PHARMA AG (DE) | 2005-12-22 | — | — | WO | disclosed |