Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 20/20 | 0.52 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.52 |
| ▸ | CCR7 | P32248 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5568690 | 1.00 | CXCR2 (0.52) | CXCR2CXCR1CCR7 | |
| SCHEMBL1487339 | 1.00 | CXCR2 (0.52) | CXCR2CXCR1CCR7 | |
| SCHEMBL9972769 | 0.88 | CXCR2 (0.53) | CXCR2CXCR1CCR7 | |
| SCHEMBL9972768 | 0.88 | CXCR2 (0.53) | CXCR2CXCR1CCR7 | |
| SCHEMBL1487200 | 0.85 | CXCR2 (0.58) | CXCR2CXCR1CCR7 | |
| SCHEMBL14482332 | 0.83 | CXCR2 (0.52) | CXCR2CXCR1CCR7 | |
| SCHEMBL1644205 | 0.83 | CXCR2 (0.53) | CXCR2CXCR1 | |
| SCHEMBL1487391 | 0.83 | CXCR2 (0.53) | CXCR2CXCR1 | |
| SCHEMBL1487255 | 0.82 | CXCR2 (0.61) | CXCR2CXCR1CCR7 | |
| SCHEMBL1487906 | 0.82 | CXCR2 (0.59) | CXCR2CXCR1CCR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006024823-A9 | PYRIMIDINE SULPHONAMIDE DERIVATIVES AS CHEMOKINE RECEPTOR MODULATORS | ASTRAZENECA AB (SE) | 2007-03-15 | — | — | WO | disclosed |