SCHEMBL5569435

SCHEMBL5569435

C#Cc1ccc(-c2cc(-c3ccccn3)nc(-c3ccccn3)c2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CCR1 P32246 3/20 0.50
CCR5 P51681 3/20 0.50
CCR8 P51685 3/20 0.50
KDM4E B2RXH2 6/20 0.48
LMNA P02545 4/20 0.48
TP53 P04637 3/20 0.48
SMN1; SMN2 Q16637 3/20 0.48
ALOX15 P16050 2/20 0.48
HTT P42858 2/20 0.48
TDP1 Q9NUW8 2/20 0.48
L3MBTL1 Q9Y468 2/20 0.48
ALPL P05186 1/20 0.48
HSP90AA1 P07900 1/20 0.48
ALPI P09923 1/20 0.48
ALPG P10696 1/20 0.48
MAPK1 P28482 1/20 0.48
METAP1 P53582 2/20 0.45
CYP1A2 P05177 2/20 0.45
POLB P06746 1/20 0.45
BLM P54132 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31310264 1.00 CCR1 (0.50) CCR1CCR5CCR8KDM4ELMNA
SCHEMBL5564832 0.88 KDM4E (0.51) CCR1CCR5CCR8KDM4ELMNA
SCHEMBL2007559 0.86 CCR1 (0.64) CCR1CCR5CCR8KDM4ELMNA
SCHEMBL29660049 0.86 CCR1 (0.64) CCR1CCR5CCR8KDM4ELMNA
SCHEMBL13311187 0.86 CCR1 (0.64) CCR1CCR5CCR8KDM4ELMNA
SCHEMBL31310378 0.84 CCR1 (0.58) CCR1CCR5CCR8KDM4ELMNA
SCHEMBL18489879 0.84 CCR1 (0.62) CCR1CCR5CCR8KDM4ELMNA
SCHEMBL4906246 0.83 KDM4E (0.50) CCR1CCR5CCR8KDM4ELMNA
SCHEMBL2542485 0.83 CCR1 (0.60) CCR1CCR5CCR8KDM4ELMNA
SCHEMBL4951059 0.82 KDM4E (0.70) CCR1CCR5CCR8KDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10118995-B2 Organic/heterometallic hybrid polymer, process for producing same, film of organic/heterometallic hybrid polymer, organic/multimetallic hybrid polymer, process for producing same, and film of organic/multimetallic hybrid polymer NATIONAL INSTITUTE OF MATERIALS SCIENCE (JP) 2018-11-06 US disclosed
EP-3138868-B1 ORGANIC/HETEROMETALLIC HYBRID POLYMER, PROCESS FOR PRODUCING SAME, FILM OF ORGANIC/HETEROMETALLIC HYBRID POLYMER, ORGANIC/MULTIMETALLIC HYBRID POLYMER, PROCESS FOR PRODUCING SAME, AND FILM OF ORGANIC/MULTIMETALLIC HYBRID POLYMER NAT INST MATERIALS SCIENCE (JP) 2018-03-07 EP disclosed
EP-3138868-A1 ORGANIC/HETEROMETALLIC HYBRID POLYMER, PROCESS FOR PRODUCING SAME, FILM OF ORGANIC/HETEROMETALLIC HYBRID POLYMER, ORGANIC/MULTIMETALLIC HYBRID POLYMER, PROCESS FOR PRODUCING SAME, AND FILM OF ORGANIC/MULTIMETALLIC HYBRID POLYMER National Institute for Materials Science (JP) 2017-03-08 EP disclosed
US-20170044325-A1 Organic/Heterometallic Hybrid Polymer, Process for Producing Same, Film of Organic/Heterometallic Hybrid Polymer, Organic/Multimetallic Hybrid Polymer, Process for Producing Same, and Film of Organic/Multimetallic Hybrid Polymer NATIONAL INSTITUTE FOR MATERIALS SCIENCE (JP) 2017-02-16 US disclosed
US-20070276117-A1 Process for the Production of an Isotropic Polymeric Network DSM IP ASSETS B.V. (NL) 2007-11-29 US disclosed
EP-1633804-B1 PROCESS FOR THE PRODUCTION OF AN ISOTROPIC POLYMERIC NETWORK DSM IP ASSETS BV (NL) 2007-10-17 EP disclosed
EP-1486527-A1 Process for the production of an isotropic polymeric network DSM IP Assets B.V. (NL) 2004-12-15 EP disclosed