Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1486996 | 1.00 | CXCR2 (0.87) | CXCR2CXCR1 | |
| SCHEMBL1644696 | 1.00 | CXCR2 (0.87) | CXCR2CXCR1 | |
| SCHEMBL1487180 | 0.94 | CXCR2 (0.77) | CXCR2CXCR1 | |
| SCHEMBL14601156 | 0.94 | CXCR2 (0.77) | CXCR2CXCR1 | |
| SCHEMBL1645344 | 0.93 | CXCR2 (1.00) | CXCR2CXCR1 | |
| SCHEMBL345883 | 0.93 | CXCR2 (1.00) | CXCR2CXCR1 | |
| SCHEMBL1487902 | 0.93 | CXCR2 (1.00) | CXCR2CXCR1 | |
| SCHEMBL345884 | 0.93 | CXCR2 (1.00) | CXCR2CXCR1 | |
| SCHEMBL1487900 | 0.93 | CXCR2 (1.00) | CXCR2CXCR1 | |
| SCHEMBL29351624 | 0.93 | CXCR2 (1.00) | CXCR2CXCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1809624-A1 | PYRIMIDINE SULPHONAMIDE DERIVATIVES AS CHEMOKINE RECEPTOR MODULATORS | AstraZeneca AB (SE) | 2007-07-25 | — | — | EP | disclosed |
| WO-2006024823-A9 | PYRIMIDINE SULPHONAMIDE DERIVATIVES AS CHEMOKINE RECEPTOR MODULATORS | ASTRAZENECA AB (SE) | 2007-03-15 | — | — | WO | disclosed |
| WO-2006024823-A1 | PYRIMIDINE SULPHONAMIDE DERIVATIVES AS CHEMOKINE RECEPTOR MODULATORS | ASTRAZENECA AB (SE) | 2006-03-09 | — | — | WO | disclosed |