Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 20/20 | 0.54 |
| ▸ | DPP7 | Q9UHL4 | 5/20 | 0.54 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.48 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4954853 | 1.00 | DPP4 (0.54) | DPP4DPP7DPP8DPP9 | |
| SCHEMBL4957718 | 0.79 | SCN9A (0.44) | — | |
| SCHEMBL4957710 | 0.79 | SCN9A (0.44) | — | |
| SCHEMBL14307565 | 0.78 | DPP4 (0.35) | DPP4DPP7DPP8DPP9 | |
| SCHEMBL5188904 | 0.76 | DPP4 (0.53) | DPP4DPP7DPP8DPP9 | |
| SCHEMBL4917079 | 0.76 | DPP4 (0.53) | DPP4DPP7DPP8DPP9 | |
| SCHEMBL8474386 | 0.76 | DPP4 (0.65) | DPP4DPP7DPP8DPP9 | |
| SCHEMBL14006817 | 0.75 | DPP4 (0.71) | DPP4DPP7DPP8 | |
| SCHEMBL4954727 | 0.75 | DPP4 (0.55) | DPP4DPP7DPP8 | |
| SCHEMBL8483179 | 0.75 | DPP4 (0.67) | DPP4DPP7DPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1786806-A1 | DPP-IV INHIBITORS | Santhera Pharmaceuticals (Schweiz) AG (CH) | 2007-05-23 | — | — | EP | disclosed |
| WO-2005121131-A1 | DPP-IV INHIBITORS | SANTHERA PHARMACEUTICALS (SCHWEIZ) AG (CH) | 2005-12-22 | — | — | WO | disclosed |