SCHEMBL5570717

SCHEMBL5570717

C[Si](C)(C)C1=C(B(c2ccccc2)c2ccccc2)CC=C1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8468784 0.96
SCHEMBL8466314 0.95
SCHEMBL5570719 0.74
Hydrochloric Acid SCHEMBL5569727 0.72
SCHEMBL8651004 0.70
SCHEMBL7558926 0.70
SCHEMBL8661698 0.69
SCHEMBL8467650 0.67
SCHEMBL8468078 0.63
SCHEMBL6544819 0.63 CYP3A4 (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7169865-B2 Transition metal compounds having a donor-acceptor interaction and a specific substitution pattern BAYER AKTIENGESELLSCHAFT (DE) 2007-01-30 US disclosed
US-7169866-B2 Process for preparing homopolymers, copolymers and/or block copolymers by living polymerization with metallocenes having a donor-acceptor interaction BAYER AKTIENGESELLSCHAFT (DE) 2007-01-30 US disclosed
EP-1546165-A1 TRANSITION METAL COMPOUNDS WITH DONOR-ACCEPTOR INTERACTION AND A SPECIAL SUBSTITUTION PATTERN Lanxess Deutschland GmbH (DE) 2005-06-29 EP disclosed
WO-2004029065-A1 TRANSITION METAL COMPOUNDS WITH DONOR-ACCEPTOR INTERACTION AND A SPECIAL SUBSTITUTION PATTERN LANXESS DEUTSCHLAND GMBH (DE) 2004-04-08 WO disclosed
US-20040063877-A1 Process for preparing homopolymers, copolymers and/or block copolymers by living polymerization with metallocenes having a donor-acceptor interaction LANXESS DEUTSCHLAND GMBH (DE) 2004-04-01 US disclosed
US-20040059073-A1 Transition metal compounds having a donor-acceptor interaction and a specific substitution pattern LANXESS DEUTSCHLAND GMBH (DE) 2004-03-25 US disclosed