SCHEMBL5570720

SCHEMBL5570720

S=C=Nc1cccs1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11647522 0.94 MIF (0.37)
SCHEMBL28571583 0.94 MIF (0.37)
SCHEMBL546504 0.76
SCHEMBL12796947 0.76
SCHEMBL15812941 0.76
Benzene SCHEMBL20450537 0.74 DAO (0.37)
Water SCHEMBL27479326 0.74
SCHEMBL828387 0.72
SCHEMBL13667832 0.72
SCHEMBL11615951 0.71 CYP3A4 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11535713-B2 Network polymers and methods of making and using same THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) 2022-12-27 US claimed
US-20220119567-A1 NETWORK POLYMERS AND METHODS OF MAKING AND USING SAME NATIONAL SCIENCE FOUNDATION 2022-04-21 US claimed
US-20210292482-A1 NETWORK POLYMERS AND METHODS OF MAKING AND USING SAME THE REGENTS OF THE UNIV OF COLORADO A BODY CORPORTATE (US) 2021-09-23 US claimed
EP-3504251-A1 NETWORK POLYMERS AND METHODS OF MAKING AND USING SAME The Regents of the University of Colorado, a Body Corporate (US) 2019-07-03 EP claimed
CN-109265382-A A kind of fluorine-containing thiocarbamates compound and its synthetic method 湖北科技学院 2019-01-25 CN claimed
WO-2018039331-A1 NETWORK POLYMERS AND METHODS OF MAKING AND USING SAME THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) 2018-03-01 WO claimed
CN-107188866-A A kind of synthetic method of the ketone compounds of polysubstituted thiazole 4 湖北科技学院 2017-09-22 CN claimed
CN-106966990-A A kind of synthetic method of the polysubstituted ketone compounds of 2 thiocarbamoyl imidazole quinoline 4 湖北科技学院 2017-07-21 CN claimed
CN-122094934-A Polythiol composition and use thereof 2026-05-26 CN disclosed
CN-120019099-A Polythiol composition, polymerizable composition, resin, molded article, optical material, and lens 三井化学株式会社 2025-05-16 CN disclosed
CN-119998263-A Polythiol composition, polymerizable composition, resin, molded article, optical material, and lens 三井化学株式会社 2025-05-13 CN disclosed
CN-116157721-B Polythiol composition, polymerizable composition, resin, molded article, optical material, and lens 三井化学株式会社 2024-09-20 CN disclosed
CN-118620162-A Polythiol composition, polymerizable composition, resin, molded article, optical material, and lens 三井化学株式会社 2024-09-10 CN disclosed
CN-118541349-A Polythiol composition and use thereof 三井化学株式会社 2024-08-23 CN disclosed
US-5189052-A Hypotensive agent MERRELL DOW PHARMACEUTICALS INC. (US) 1993-02-23 US disclosed
US-5057613-A Hypotensive agents MERRELL DOW PHARMACEUTICALS (US) 1991-10-15 US disclosed
US-4810800-A HYPOTENSIVE AGENTS MERRELL DOW PHARMACEUTICALS INC. (US) 1989-03-07 US disclosed
EP-0244803-A2 Novel dopamine beta hydroxylase inhibitors MERRELL DOW PHARMACEUTICALS INC. (US) 1987-11-11 EP disclosed
US-4363909-A ANTIVIRAL AGENTS RHONE POULENC INDUSTRIES (FR) 1982-12-14 US disclosed
US-4177279-A 1-[(3-Indolyl)-alkyl]-piperidyl ureas and hypotensive compositions JOHN WYETH & BROTHER LTD. (GB) 1979-12-04 US disclosed