Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.53 |
| ▸ | UTS2R | Q9UKP6 | 9/20 | 0.50 |
| ▸ | CNR1 | P21554 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | EP300 | Q09472 | 2/20 | 0.42 |
| ▸ | CASR | P41180 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5570567 | 0.90 | CNR1 (0.52) | EPHX2UTS2RCNR1MAPTEP300 | |
| SCHEMBL5570302 | 0.86 | SLC6A2 (0.48) | EPHX2UTS2RCNR1MAPTEP300 | |
| SCHEMBL5570583 | 0.85 | CNR1 (0.50) | EPHX2UTS2RCNR1MAPTEP300 | |
| SCHEMBL5565619 | 0.82 | CNR1 (0.51) | EPHX2CNR1MAPTHRH3EP300 | |
| SCHEMBL5567514 | 0.79 | EPHX2 (0.48) | EPHX2CNR1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL5570803 | 0.78 | F10 (0.40) | EPHX2UTS2RCNR1EP300 | |
| SCHEMBL5671937 | 0.77 | CNR1 (0.46) | UTS2RCNR1MAPTEP300CASR | |
| SCHEMBL5670191 | 0.77 | MAPT (0.45) | UTS2RCNR1MAPTEP300CASR | |
| SCHEMBL6376149 | 0.76 | MEN1 (0.59) | UTS2RCNR1MAPTCASRMEN1 | |
| SCHEMBL6376157 | 0.76 | MEN1 (0.59) | UTS2RCNR1MAPTCASRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7250415-B2 | 1,1-Disubstitutedcycloalkyl-, glycinamidyl-, sulfonyl-amidino-, and tetrahydropyrimidinyl-containing diaminoalkyl, β-aminoacids, α-aminoacids and derivatives thereof as factor Xa inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-07-31 | — | — | US | disclosed |
| EP-1628668-A2 | 1,1-DISUBSTITUTEDCYCLOALKYL-, GLYCINAMIDYL-, SULFONYL-AMIDINO-, AND TETRAHYDROPYRIMIDINYL-CONTAINING DIAMINOALKYL, BETA-AMINOACIDS, ALPHA-AMINOACIDS AND DERIVATIVES THEREOF AS FACTOR XA INHIBITO RS | Bristol-Myers Squibb Company (US) | 2006-03-01 | — | — | EP | disclosed |
| WO-2004108892-A2 | 1,1-DISUBSTITUTEDCYCLOALKYL-, GLYCINAMIDYL-, SULFONYL-AMIDINO-, AND TETRAHYDROPYRIMIDINYL-CONTAINING DIAMINOALKYL, β-AMINOACIDS, α-AMINOACIDS AND DERIVATIVES THEREOF AS FACTOR XA INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-12-16 | — | — | WO | disclosed |