Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNFRSF1A | P19438 | 8/20 | 0.66 |
| ▸ | ABCG2 | Q9UNQ0 | 5/20 | 0.55 |
| ▸ | ACHE | P22303 | 1/20 | 0.55 |
| ▸ | MAOB | P27338 | 1/20 | 0.55 |
| ▸ | PDE4A | P27815 | 1/20 | 0.53 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.53 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.53 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | AR | P10275 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5571695 | 0.90 | TNFRSF1A (0.69) | TNFRSF1AABCG2MEN1KMT2AMAPT | |
| SCHEMBL5574920 | 0.90 | TNFRSF1A (0.69) | TNFRSF1AABCG2MEN1KMT2AMAPT | |
| SCHEMBL5571802 | 0.80 | TNFRSF1A (1.00) | TNFRSF1AABCG2 | |
| SCHEMBL5571804 | 0.80 | TNFRSF1A (1.00) | TNFRSF1AABCG2 | |
| SCHEMBL5574930 | 0.78 | TNFRSF1A (1.00) | TNFRSF1A | |
| SCHEMBL5574927 | 0.78 | TNFRSF1A (1.00) | TNFRSF1A | |
| SCHEMBL5575692 | 0.78 | TNFRSF1A (0.73) | TNFRSF1AABCG2MAPT | |
| SCHEMBL5575927 | 0.78 | TNFRSF1A (0.73) | TNFRSF1AABCG2MAPT | |
| SCHEMBL4728448 | 0.78 | TNFRSF1A (0.75) | TNFRSF1AABCG2MAOBAR | |
| SCHEMBL4728450 | 0.78 | TNFRSF1A (0.75) | TNFRSF1AABCG2MAOBAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7247714-B2 | Protection against oxidative stress and inflammation by a cytoprotective response element | ATHEROGENICS, INC. (US) | 2007-07-24 | — | — | US | disclosed |