Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1487020 | 1.00 | KDM4E (0.31) | KDM4ETSHR | |
| SCHEMBL5241702 | 0.90 | KDM4E (0.34) | KDM4E | |
| SCHEMBL4420207 | 0.88 | MAPK1 (0.32) | — | |
| SCHEMBL2962445 | 0.82 | TSHR (0.32) | TSHR | |
| SCHEMBL3608074 | 0.82 | TSHR (0.32) | TSHR | |
| SCHEMBL1628831 | 0.82 | TSHR (0.32) | TSHR | |
| SCHEMBL14762534 | 0.80 | USP2 (0.56) | — | |
| SCHEMBL9069638 | 0.80 | USP2 (0.56) | — | |
| SCHEMBL6113475 | 0.80 | USP2 (0.56) | — | |
| SCHEMBL28854872 | 0.80 | USP2 (0.56) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1809624-A1 | PYRIMIDINE SULPHONAMIDE DERIVATIVES AS CHEMOKINE RECEPTOR MODULATORS | AstraZeneca AB (SE) | 2007-07-25 | — | — | EP | disclosed |
| WO-2006024823-A9 | PYRIMIDINE SULPHONAMIDE DERIVATIVES AS CHEMOKINE RECEPTOR MODULATORS | ASTRAZENECA AB (SE) | 2007-03-15 | — | — | WO | disclosed |
| WO-2006024823-A1 | PYRIMIDINE SULPHONAMIDE DERIVATIVES AS CHEMOKINE RECEPTOR MODULATORS | ASTRAZENECA AB (SE) | 2006-03-09 | — | — | WO | disclosed |