Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 18/20 | 0.42 |
| ▸ | TLR8 | Q9NR97 | 10/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CRHBP | P24387 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.34 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1232558 | 0.86 | TLR7 (0.46) | TLR7TLR8MEN1MAPTTSHR | |
| SCHEMBL1232808 | 0.85 | TLR7 (0.46) | TLR7TLR8MEN1MAPTTSHR | |
| SCHEMBL1232410 | 0.83 | TLR7 (0.51) | TLR7TLR8MEN1MAPTTSHR | |
| SCHEMBL1233708 | 0.82 | TLR7 (0.42) | TLR7TLR8MEN1MAPTTSHR | |
| SCHEMBL1232471 | 0.82 | TLR7 (0.42) | TLR7TLR8MEN1MAPTTSHR | |
| SCHEMBL1233793 | 0.81 | TLR7 (0.42) | TLR7TLR8NUDT1 | |
| SCHEMBL1233234 | 0.81 | TLR7 (0.48) | TLR7TLR8MEN1MAPTTSHR | |
| SCHEMBL1233720 | 0.81 | TLR7 (0.40) | TLR7TLR8ADORA3ADORA2A | |
| SCHEMBL1233851 | 0.81 | TLR7 (0.53) | TLR7TLR8MEN1MAPTKMT2A | |
| SCHEMBL1776731 | 0.79 | TLR7 (0.42) | TLR7TLR8MEN1MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1863809-A2 | PYRAZOLOPYRIDINES AND ANALOGS THEREOF | Coley Pharmaceutical Group, Inc. (US) | 2007-12-12 | — | — | EP | disclosed |
| WO-2006107753-A2 | PYRAZOLOPYRIDINES AND ANALOGS THEREOF | COLEY PHARMACEUTICAL GROUP, INC. (US) | 2006-10-12 | — | — | WO | disclosed |