Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 19/20 | 0.56 |
| ▸ | F2 | P00734 | 4/20 | 0.56 |
| ▸ | KLK1 | P06870 | 4/20 | 0.56 |
| ▸ | TMPRSS15 | P98073 | 15/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3232998 | 0.91 | PRSS1 (0.58) | PRSS1F2KLK1TMPRSS15 | |
| SCHEMBL3245126 | 0.86 | PRSS1 (0.66) | PRSS1F2KLK1TMPRSS15 | |
| SCHEMBL7304838 | 0.86 | PRSS1 (0.66) | PRSS1F2KLK1TMPRSS15 | |
| SCHEMBL3237141 | 0.85 | PRSS1 (0.67) | PRSS1F2KLK1TMPRSS15 | |
| SCHEMBL7518605 | 0.85 | PRSS1 (0.59) | PRSS1F2KLK1TMPRSS15 | |
| SCHEMBL7518598 | 0.85 | PRSS1 (0.59) | PRSS1F2KLK1TMPRSS15 | |
| SCHEMBL3241353 | 0.81 | PRSS1 (0.69) | PRSS1F2KLK1TMPRSS15 | |
| SCHEMBL3237729 | 0.79 | PRSS1 (0.69) | PRSS1F2KLK1TMPRSS15 | |
| SCHEMBL3241766 | 0.78 | PRSS1 (0.70) | PRSS1F2KLK1TMPRSS15 | |
| SCHEMBL3231286 | 0.77 | PRSS1 (0.80) | PRSS1F2KLK1TMPRSS15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1815865-A1 | THERAPEUTIC AGENT FOR DIABETES COMPRISING PROTEASE-INHIBITING COMPOUND | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-08-08 | — | — | EP | disclosed |