Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 11/20 | 0.61 |
| ▸ | F2 | P00734 | 5/20 | 0.61 |
| ▸ | KLK1 | P06870 | 4/20 | 0.61 |
| ▸ | TMPRSS15 | P98073 | 11/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.38 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | PLG | P00747 | 1/20 | 0.38 |
| ▸ | F12 | P00748 | 1/20 | 0.38 |
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
| ▸ | PLAT | P00750 | 1/20 | 0.38 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3240729 | 0.97 | PRSS1 (0.59) | PRSS1F2KLK1TMPRSS15MEN1 | |
| SCHEMBL3230753 | 0.96 | PRSS1 (0.58) | PRSS1F2KLK1TMPRSS15MEN1 | |
| SCHEMBL3237775 | 0.96 | PRSS1 (0.58) | PRSS1F2KLK1TMPRSS15MEN1 | |
| SCHEMBL3240050 | 0.95 | PRSS1 (0.63) | PRSS1F2KLK1TMPRSS15MEN1 | |
| SCHEMBL7311823 | 0.94 | PRSS1 (0.60) | PRSS1F2KLK1TMPRSS15MEN1 | |
| SCHEMBL3233274 | 0.94 | PRSS1 (0.58) | PRSS1F2KLK1TMPRSS15MEN1 | |
| SCHEMBL7315085 | 0.94 | PRSS1 (0.58) | PRSS1F2KLK1TMPRSS15MEN1 | |
| SCHEMBL3237754 | 0.91 | PRSS1 (0.58) | PRSS1F2KLK1TMPRSS15MEN1 | |
| SCHEMBL3237746 | 0.91 | PRSS1 (0.58) | PRSS1F2KLK1TMPRSS15MEN1 | |
| SCHEMBL3245435 | 0.91 | PRSS1 (0.58) | PRSS1F2KLK1TMPRSS15MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1815865-A1 | THERAPEUTIC AGENT FOR DIABETES COMPRISING PROTEASE-INHIBITING COMPOUND | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-08-08 | — | — | EP | disclosed |