Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | THPO | P40225 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | CTSD | P07339 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.35 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.35 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL439778 | 0.83 | APP (0.41) | APPTSHRMAPTCYP1A2CYP3A4 | |
| SCHEMBL1663500 | 0.83 | APP (0.41) | APPTSHRMAPTCYP1A2CYP3A4 | |
| SCHEMBL3030029 | 0.83 | APP (0.41) | APPTSHRMAPTCYP1A2CYP3A4 | |
| SCHEMBL3033536 | 0.79 | APP (0.38) | APPTSHRMAPT | |
| SCHEMBL27531752 | 0.77 | MAOB (0.56) | MAPTCYP1A2CYP2C9ALDH1A1NPC1 | |
| SCHEMBL2639345 | 0.77 | APP (0.36) | APPTSHRMAPTALDH1A1 | |
| SCHEMBL3035853 | 0.77 | APP (0.36) | APPTSHR | |
| SCHEMBL28383708 | 0.77 | MAOB (0.56) | MAPTCYP1A2CYP2C9ALDH1A1NPC1 | |
| SCHEMBL123465 | 0.75 | — | — | |
| SCHEMBL5933769 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7169865-B2 | Transition metal compounds having a donor-acceptor interaction and a specific substitution pattern | BAYER AKTIENGESELLSCHAFT (DE) | 2007-01-30 | — | — | US | disclosed |
| US-7169866-B2 | Process for preparing homopolymers, copolymers and/or block copolymers by living polymerization with metallocenes having a donor-acceptor interaction | BAYER AKTIENGESELLSCHAFT (DE) | 2007-01-30 | — | — | US | disclosed |
| EP-1549683-A1 | METHOD FOR PRODUCING HOMOPOLYMERS, COPOLYMERS AND/OR BLOCK COPOLYMERS COMPRISING METALLOCENES WITH A DONOR-ACCEPTOR INTERACTION, ACCORDING TO A LIVING POLYMERISATION PROCESS | Lanxess Deutschland GmbH (DE) | 2005-07-06 | — | — | EP | disclosed |
| EP-1546165-A1 | TRANSITION METAL COMPOUNDS WITH DONOR-ACCEPTOR INTERACTION AND A SPECIAL SUBSTITUTION PATTERN | Lanxess Deutschland GmbH (DE) | 2005-06-29 | — | — | EP | disclosed |
| WO-2004029100-A1 | METHOD FOR PRODUCING HOMOPOLYMERS, COPOLYMERS AND/OR BLOCK COPOLYMERS COMPRISING METALLOCENES WITH A DONOR-ACCEPTOR INTERACTION, ACCORDING TO A LIVING POLYMERISATION PROCESS | LANXESS DEUTSCHLAND GMBH (DE) | 2004-04-08 | — | — | WO | disclosed |
| WO-2004029065-A1 | TRANSITION METAL COMPOUNDS WITH DONOR-ACCEPTOR INTERACTION AND A SPECIAL SUBSTITUTION PATTERN | LANXESS DEUTSCHLAND GMBH (DE) | 2004-04-08 | — | — | WO | disclosed |
| US-20040063877-A1 | Process for preparing homopolymers, copolymers and/or block copolymers by living polymerization with metallocenes having a donor-acceptor interaction | LANXESS DEUTSCHLAND GMBH (DE) | 2004-04-01 | — | — | US | disclosed |
| US-20040059073-A1 | Transition metal compounds having a donor-acceptor interaction and a specific substitution pattern | LANXESS DEUTSCHLAND GMBH (DE) | 2004-03-25 | — | — | US | disclosed |
| EP-1041086-B1 | Supported catalysts with donor-acceptor interaction | BAYER AG (DE) | 2004-02-18 | — | — | EP | disclosed |
| EP-1373284-A1 | CATALYSTS CHARACTERIZED BY A DONOR-ACCEPTOR INTERACTION | Bayer Aktiengesellschaft (DE) | 2004-01-02 | — | — | EP | disclosed |
| EP-0912585-A1 | METALLOCENE COMPOUNDS | BAYER AG (DE) | 1999-05-06 | — | — | EP | disclosed |
| EP-0909284-A1 | METHOD FOR PRODUCING THERMOPLASTIC ELASTOMERS | BAYER AG (DE) | 1999-04-21 | — | — | EP | disclosed |
| EP-0909281-A1 | METHOD FOR PRODUCING ELASTOMERS | BAYER AG (DE) | 1999-04-21 | — | — | EP | disclosed |
| EP-0909282-A1 | METHOD FOR PRODUCING CYCLOOLEFIN (CO)POLYMERS FOR TECHNICAL APPLICATIONS | BAYER AG (DE) | 1999-04-21 | — | — | EP | disclosed |
| WO-1998001487-A9 | METHOD FOR PRODUCING ELASTOMERS | — | 1998-07-02 | — | — | WO | disclosed |
| WO-1998001486-A9 | METHOD FOR PRODUCING THERMOPLASTIC ELASTOMERS | — | 1998-03-26 | — | — | WO | disclosed |
| WO-1998001455-A1 | METALLOCENE COMPOUNDS | BAYER AKTIENGESELLSCHAFT (DE) | 1998-01-15 | — | — | WO | disclosed |
| WO-1998001486-A1 | METHOD FOR PRODUCING THERMOPLASTIC ELASTOMERS | BAYER AKTIENGESELLSCHAFT (DE) | 1998-01-15 | — | — | WO | disclosed |
| WO-1998001484-A1 | METHOD FOR PRODUCING CYCLOOLEFIN (CO)POLYMERS FOR TECHNICAL APPLICATIONS | BAYER AKTIENGESELLSCHAFT (DE) | 1998-01-15 | — | — | WO | disclosed |
| WO-1998001487-A1 | METHOD FOR PRODUCING ELASTOMERS | BAYER AKTIENGESELLSCHAFT (DE) | 1998-01-15 | — | — | WO | disclosed |