Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 11/20 | 0.51 |
| ▸ | ITGA4 | P13612 | 11/20 | 0.51 |
| ▸ | PPARG | P37231 | 6/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2982542 | 1.00 | ITGB1 (0.51) | ITGB1ITGA4PPARGFFAR1DRD1 | |
| SCHEMBL5147510 | 0.91 | ITGB1 (0.44) | ITGB1ITGA4FFAR1DRD1 | |
| SCHEMBL2978167 | 0.89 | ITGB1 (0.45) | ITGB1ITGA4PPARGFFAR1DRD1 | |
| SCHEMBL2978173 | 0.89 | ITGB1 (0.45) | ITGB1ITGA4PPARGFFAR1DRD1 | |
| SCHEMBL2978120 | 0.89 | ITGB1 (0.42) | ITGB1ITGA4PPARGFFAR1DRD1 | |
| SCHEMBL2974021 | 0.86 | ITGB1 (0.54) | ITGB1ITGA4PPARG | |
| SCHEMBL7265369 | 0.86 | ITGB1 (0.54) | ITGB1ITGA4PPARG | |
| SCHEMBL2980127 | 0.84 | ITGB1 (0.53) | ITGB1ITGA4 | |
| SCHEMBL5147594 | 0.83 | PPARG (0.44) | ITGB1ITGA4PPARGFFAR1DRD1 | |
| SCHEMBL5147512 | 0.82 | FFAR1 (0.38) | ITGB1ITGA4FFAR1DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1780201-A2 | PHENYLALANINE ENAMIDE DERIVATIVES POSSESSING A CYCLOBUTENE GROUP, FOR USE AS INTEGRIN INHIBITORS | Celltech R&D Limited (GB) | 2007-05-02 | — | — | EP | disclosed |