Known targets — ChEMBL curated mechanism
CHRM1DRD2DRD3DRD4HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR2APDE3ASIGMAR1SLC9A3
The experimentally established mechanism targets of L-Lactic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 known ✓ | O15379 | 2/20 | 0.33 |
| ▸ | HDAC1 known ✓ | Q13547 | 2/20 | 0.33 |
| ▸ | HDAC2 known ✓ | Q92769 | 2/20 | 0.33 |
| ▸ | HDAC8 known ✓ | Q9BY41 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | BBOX1 | O75936 | 5/20 | 0.38 |
| ▸ | SLC22A16 | Q86VW1 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5575052 | 0.88 | CYP3A4 (0.41) | TSHRCYP3A4NFKB1NPSR1CA1 | |
| Tributylmethylammonium SCHEMBL5570483 | 0.87 | CA1 (0.45) | TSHRCYP3A4NFKB1NPSR1CA1 | |
| L-Lactic Acid SCHEMBL4956025 | 0.86 | SLC22A16 (0.40) | TSHRCYP3A4NFKB1NPSR1CA1 | |
| L-Lactic Acid SCHEMBL5571673 | 0.85 | CA1 (0.48) | NFKB1CA1BBOX1CA2 | |
| Lactic Acid SCHEMBL5574271 | 0.84 | TP53 (0.52) | TSHRCA2HDAC1HDAC2 | |
| Tetrapropylammonium SCHEMBL5574321 | 0.84 | SLC22A1 (0.48) | TSHRCYP3A4NFKB1NPSR1CA1 | |
| L-Lactic Acid SCHEMBL5574997 | 0.84 | CA1 (0.47) | CA1BBOX1CA2 | |
| L-Lactic Acid SCHEMBL5574226 | 0.84 | CA1 (0.47) | CA1BBOX1CA2 | |
| L-Lactic Acid SCHEMBL5570513 | 0.84 | CA1 (0.47) | CA1BBOX1CA2 | |
| L-Lactic Acid SCHEMBL5570538 | 0.84 | CA1 (0.47) | CA1BBOX1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070135565-A1 | COMPOSITION FOR FORMING POROUS FILM, POROUS FILM AND METHOD FOR FORMING THE SAME, INTERLEVEL INSULATOR FILM, AND SEMICONDUCTOR DEVICE | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 2007-06-14 | — | — | US | disclosed |
| US-7132473-B2 | Composition for forming porous film, porous film and method for forming the same, interlevel insulator film, and semiconductor device | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 2006-11-07 | — | — | US | disclosed |
| EP-1568744-A1 | COMPOSITION FOR POROUS FILM FORMATION, POROUS FILM, PROCESS FOR PRODUCING THE SAME, INTERLAYER INSULATION FILM AND SEMICONDUCTOR DEVICE | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 2005-08-31 | — | — | EP | disclosed |
| US-20040219372-A1 | Composition for forming porous film, porous film and method for forming the same, interlevel insulator film, and semiconductor device | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. | 2004-11-04 | — | — | US | disclosed |