Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7474377 | 0.84 | NQO2 (0.56) | NQO2MEN1KMT2AHRH4CYP1A2 | |
| SCHEMBL804981 | 0.76 | TSHR (0.61) | NQO2MEN1KMT2AHRH4CYP1A2 | |
| SCHEMBL5096456 | 0.75 | MAPT (0.62) | NQO2MEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL6873559 | 0.74 | NQO2 (0.47) | NQO2MEN1KMT2AHRH4CYP1A2 | |
| SCHEMBL2178510 | 0.74 | TDP1 (0.58) | NQO2MEN1KMT2AHRH4L3MBTL1 | |
| SCHEMBL12498159 | 0.74 | NQO2 (0.47) | NQO2MEN1KMT2AHRH4CYP1A2 | |
| SCHEMBL4684319 | 0.74 | KDM4E (0.58) | NQO2MEN1KMT2AHRH4CYP1A2 | |
| SCHEMBL14624137 | 0.74 | NQO2 (0.52) | NQO2MEN1KMT2AHRH4CYP1A2 | |
| SCHEMBL22929108 | 0.74 | NQO2 (0.47) | NQO2MEN1KMT2AHRH4CYP1A2 | |
| SCHEMBL18023061 | 0.74 | TLR8 (0.49) | NQO2MEN1KMT2AHRH4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1819698-A1 | 1-[(6,7-SUBSTITUTED ALKOXYQUINOXALINYL)AMINOCARBONYL]-4-(HETERO)ARYLPIPERAZINE DERIVATIVES | Rexahn Pharmaceuticals, Inc. (US) | 2007-08-22 | — | — | EP | disclosed |
| WO-2006054830-A1 | 1-[(6,7-SUBSTITUTED ALKOXYQUINOXALINYL)AMINOCARBONYL]-4-(HETERO)ARYLPIPERAZINE DERIVATIVES | REXAHN PHARMACEUTICALS, INC. (US) | 2006-05-26 | — | — | WO | disclosed |