Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.59 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.59 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.59 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.59 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.59 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.59 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.59 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.59 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.59 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.59 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | HPGD | P15428 | 5/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5574642 | 1.00 | HDAC8 (0.59) | HDAC8HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL21959256 | 1.00 | HDAC8 (0.59) | HDAC8HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL3468449 | 0.91 | HDAC8 (0.69) | HDAC8HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL607631 | 0.91 | HDAC8 (0.69) | HDAC8HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL9350109 | 0.91 | HDAC8 (0.69) | HDAC8HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL3468927 | 0.91 | HDAC8 (0.69) | HDAC8HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL9899475 | 0.91 | HDAC8 (0.69) | HDAC8HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL4202491 | 0.91 | HDAC8 (0.69) | HDAC8HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL133529 | 0.91 | HDAC8 (0.69) | HDAC8HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL9130049 | 0.91 | HDAC8 (0.69) | HDAC8HDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1755684-B1 | ALBUMIN-BINDING CONJUGATES COMPRISING A FATTY ACID AND PEG | UCB BIOPHARMA SPRL (BE) | 2016-08-31 | — | — | EP | disclosed |
| EP-1755684-A2 | ALBUMIN-BINDING CONJUGATES COMPRISING A FATTY ACID AND PEG | Celltech R&D Limited (GB) | 2007-02-28 | — | — | EP | disclosed |
| WO-2005117984-A2 | ALBUMIN-BINDING CONJUGATES COMPRISING A FATTY ACID AND PEG | CELLTECH R & D LIMITED (GB) | 2005-12-15 | — | — | WO | disclosed |