Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLP1R | P43220 | 8/20 | 0.66 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.41 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.38 |
| ▸ | TLR2 | O60603 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | DGAT1 | O75907 | 4/20 | 0.37 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.36 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5575229 | 1.00 | GLP1R (0.66) | GLP1RC3AR1NOD1FOLH1TLR2 | |
| SCHEMBL13699565 | 0.92 | GLP1R (0.59) | GLP1RC3AR1NOD1TLR2MEN1 | |
| SCHEMBL13699566 | 0.91 | GLP1R (0.58) | GLP1RTLR2MEN1KMT2ASIRT6 | |
| SCHEMBL3485679 | 0.91 | GLP1R (0.56) | GLP1RTLR2MEN1KMT2ASIRT6 | |
| SCHEMBL3485672 | 0.91 | GLP1R (0.56) | GLP1RTLR2MEN1KMT2ASIRT6 | |
| SCHEMBL13936570 | 0.91 | GLP1R (0.56) | GLP1RTLR2MEN1KMT2ASIRT6 | |
| SCHEMBL16326834 | 0.91 | GLP1R (0.61) | GLP1RTLR2MEN1KMT2ASIRT6 | |
| SCHEMBL19513194 | 0.90 | GLP1R (0.55) | GLP1RC3AR1FOLH1DGAT1 | |
| SCHEMBL19513272 | 0.90 | GLP1R (0.55) | GLP1RC3AR1FOLH1DGAT1 | |
| SCHEMBL16326832 | 0.90 | GLP1R (0.56) | GLP1RC3AR1TLR2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1853321-A2 | INSULINOTROPIC AGENTS CONJUGATED WITH STRUCTURALLY WELL DEFINED BRANCHED POLYMERS | NOVO NORDISK A/S (DK) | 2007-11-14 | — | — | EP | disclosed |
| WO-2006087354-A2 | INSULINOTROPIC AGENTS CONJUGATED WITH STRUCTURALLY WELL DEFINED BRANCHED POLYMERS | NOVO NORDISK A/S (DK) | 2006-08-24 | — | — | WO | disclosed |