Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR2 | O95136 | 6/20 | 0.43 |
| ▸ | S1PR4 | O95977 | 6/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 6/20 | 0.43 |
| ▸ | S1PR3 | Q99500 | 6/20 | 0.43 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.43 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.42 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.42 |
| ▸ | TYMS | P04818 | 1/20 | 0.41 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.35 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11436532 | 0.88 | TYMS (0.52) | S1PR2S1PR4S1PR1S1PR3S1PR5 | |
| SCHEMBL4427913 | 0.79 | — | — | |
| SCHEMBL7880658 | 0.77 | TYMS (0.55) | S1PR2S1PR4S1PR1S1PR3S1PR5 | |
| SCHEMBL4533447 | 0.74 | HDAC8 (0.65) | LPAR3LPAR2TYMSLPAR1CYP3A4 | |
| SCHEMBL4526066 | 0.74 | HDAC8 (0.65) | LPAR3LPAR2TYMSLPAR1CYP3A4 | |
| SCHEMBL4529043 | 0.74 | HDAC8 (0.65) | LPAR3LPAR2TYMSLPAR1CYP3A4 | |
| SCHEMBL4517290 | 0.74 | HDAC8 (0.65) | LPAR3LPAR2TYMSLPAR1CYP3A4 | |
| SCHEMBL4536787 | 0.74 | HDAC8 (0.65) | LPAR3LPAR2TYMSLPAR1CYP3A4 | |
| SCHEMBL4517056 | 0.74 | HDAC8 (0.65) | LPAR3LPAR2TYMSLPAR1CYP3A4 | |
| SCHEMBL4535595 | 0.74 | HDAC8 (0.65) | LPAR3LPAR2TYMSLPAR1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007019478-A2 | DRUG DELIVERY FROM IMPLANTS USING SELF-ASSEMBLED MONOLAYERS - THERAPEUTIC SAMS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2007-02-15 | — | — | WO | disclosed |