Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2980147 | 1.00 | ITGB1 (0.62) | ITGB1ITGA4 | |
| SCHEMBL2974001 | 0.99 | ITGB1 (0.62) | ITGB1ITGA4 | |
| SCHEMBL5573483 | 0.99 | ITGB1 (0.62) | ITGB1ITGA4 | |
| SCHEMBL2978146 | 0.99 | ITGB1 (0.62) | ITGB1ITGA4 | |
| SCHEMBL2979018 | 0.94 | ITGB1 (0.58) | ITGB1ITGA4 | |
| SCHEMBL7259860 | 0.93 | ITGB1 (0.65) | ITGB1ITGA4 | |
| SCHEMBL2982307 | 0.93 | ITGB1 (0.65) | ITGB1ITGA4 | |
| SCHEMBL2980256 | 0.92 | ITGB1 (0.63) | ITGB1ITGA4 | |
| SCHEMBL2982318 | 0.92 | ITGB1 (0.64) | ITGB1ITGA4 | |
| SCHEMBL7259871 | 0.92 | ITGB1 (0.64) | ITGB1ITGA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1370531-A1 | PHENYLALANINE ENAMIDE DERIVATIVES POSSESSING A CYCLOBUTENE GROUP, FOR USE AS INTEGRIN INHIBITORS | Celltech R & D Limited (GB) | 2003-12-17 | — | — | EP | claimed |
| WO-2002068393-A1 | PHENYLALANINE ENAMIDE DERIVATIVES POSSESSING A CYCLOBUTENE GROUP, FOR USE AS INTEGRIN INHIBITORS | CELLTECH R & D LIMITED (GB) | 2002-09-06 | — | — | WO | claimed |
| EP-1370531-B1 | PHENYLALANINE ENAMIDE DERIVATIVES POSSESSING A CYCLOBUTENE GROUP, FOR USE AS INTEGRIN INHIBITORS | CELLTECH R&D LTD (GB) | 2007-02-28 | — | — | EP | disclosed |