Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 7/20 | 0.51 |
| ▸ | PTGER2 | P43116 | 6/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | DHODH | Q02127 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4087328 | 0.91 | PTGER4 (0.44) | PTGER4PTGER2MEN1KMT2AMRGPRX4 | |
| SCHEMBL4087365 | 0.86 | PTGER4 (0.49) | PTGER4PTGER2MEN1KMT2ANLRP3 | |
| SCHEMBL4081976 | 0.84 | PTGER4 (0.72) | PTGER4PTGER2 | |
| SCHEMBL27717957 | 0.84 | KMT2A (0.47) | PTGER4PTGER2MEN1KMT2AEPHX1 | |
| SCHEMBL28771821 | 0.83 | KMT2A (0.48) | PTGER4PTGER2MEN1KMT2AEPHX1 | |
| SCHEMBL4086039 | 0.81 | PTGER4 (0.42) | PTGER4PTGER2MEN1KMT2AHDAC1 | |
| SCHEMBL4087358 | 0.80 | PTGER4 (0.55) | PTGER4PTGER2MEN1KMT2A | |
| SCHEMBL4087532 | 0.78 | MAOB (0.44) | PTGER4PTGER2MEN1KMT2ANR4A2 | |
| SCHEMBL4077760 | 0.78 | PTGER4 (0.82) | PTGER4PTGER2 | |
| SCHEMBL13561187 | 0.77 | MRGPRX4 (0.56) | MEN1KMT2ANR4A2MRGPRX4KDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1847533-A1 | SIX-MEMBERED HETEROCYCLIC COMPOUND AND THE USE THEREOF | Asahi Kasei Pharma Corporation (JP) | 2007-10-24 | — | — | EP | disclosed |