Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 20/20 | 0.76 |
| ▸ | BCR | P11274 | 18/20 | 0.76 |
| ▸ | LYN | P07948 | 5/20 | 0.64 |
| ▸ | KIT | P10721 | 7/20 | 0.61 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.61 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.61 |
| ▸ | SRC | P12931 | 2/20 | 0.61 |
| ▸ | SYK | P43405 | 2/20 | 0.61 |
| ▸ | ABL2 | P42684 | 2/20 | 0.61 |
| ▸ | PLK4 | O00444 | 1/20 | 0.61 |
| ▸ | DDX3X | O00571 | 1/20 | 0.61 |
| ▸ | GAK | O14976 | 1/20 | 0.61 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.61 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.61 |
| ▸ | CA12 | O43570 | 1/20 | 0.61 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.61 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.61 |
| ▸ | EGFR | P00533 | 1/20 | 0.61 |
| ▸ | CA1 | P00915 | 1/20 | 0.61 |
| ▸ | CA2 | P00918 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4894017 | 0.86 | ABL1 (0.95) | ABL1BCRLYNKITPDGFRB | |
| SCHEMBL3557490 | 0.86 | ABL1 (1.00) | ABL1BCRLYNKITPDGFRB | |
| SCHEMBL988910 | 0.85 | ABL1 (0.82) | ABL1BCRLYNKITPDGFRB | |
| SCHEMBL4890238 | 0.84 | ABL1 (1.00) | ABL1BCRLYNKITPDGFRB | |
| SCHEMBL3799174 | 0.80 | ABL1 (0.77) | ABL1BCRLYNKITPDGFRB | |
| SCHEMBL3562355 | 0.80 | ABL1 (0.88) | ABL1BCRLYNKITPDGFRB | |
| SCHEMBL988987 | 0.80 | ABL1 (0.73) | ABL1BCRLYNKITPDGFRB | |
| SCHEMBL3567918 | 0.79 | ABL1 (0.88) | ABL1BCRLYNKITPDGFRB | |
| SCHEMBL2624946 | 0.79 | ABL1 (1.00) | ABL1BCRLYNKITPDGFRB | |
| Hydrochloric Acid SCHEMBL3566618 | 0.79 | ABL1 (0.87) | ABL1BCRLYNKITPDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1840122-A1 | AMINOPYRIMIDINE COMPOUNDS AND THEIR SALTS, PROCESS FOR PREPARATION AND PHARMACEUTICAL USE THEREOF | Sun, Piaoyang (CN) | 2007-10-03 | — | — | EP | disclosed |