SCHEMBL557624

SCHEMBL557624

[CH2]NCCN

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8536440 0.79
SCHEMBL1488493 0.77
SCHEMBL6222181 0.74
SCHEMBL14645874 0.72
SCHEMBL7451958 0.71
Ethylene SCHEMBL10687566 0.67
Ethylene SCHEMBL28942401 0.67 CA12 (0.83)
Formaldehyde SCHEMBL4430718 0.64
SCHEMBL15381 0.64
SCHEMBL284681 0.64

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 487 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3564330-B1 COATING AGENT AND MEDICAL INSTRUMENT SURFACE-TREATED WITH SAID COATING AGENT TERUMO CORP (JP) 2023-12-27 EP claimed
EP-4135683-A1 THERAPEUTIC USE OF PLEUROMUTILINS Nabriva Therapeutics GMBH (AT) 2023-02-22 EP claimed
WO-2021209596-A1 THERAPEUTIC USE OF PLEUROMUTILINS Nabriva Therapeutics GmbH (AT) 2021-10-21 WO claimed
US-11136519-B2 Coating agent and medical instrument surface-treated with said coating agent TERUMO KABUSHIKI KAISHA (JP) 2021-10-05 US claimed
US-10576188-B2 Coating agent and medical instrument surface treated with coating agent TERUMO KABUSHIKI KAISHA (JP) 2020-03-03 US claimed
EP-3318614-B1 COATING AGENT AND MEDICAL INSTRUMENT SURFACE TREATED WITH COATING AGENT TERUMO CORP (JP) 2020-02-19 EP claimed
US-10556041-B2 Coating agent and medical instrument surface treated with coating agent TERUMO KABUSHIKI KAISHA (JP) 2020-02-11 US claimed
EP-3564330-A1 COATING AGENT AND MEDICAL INSTRUMENT SURFACE-TREATED WITH SAID COATING AGENT Terumo Kabushiki Kaisha (JP) 2019-11-06 EP claimed
US-20190316055-A1 COATING AGENT AND MEDICAL INSTRUMENT SURFACE-TREATED WITH SAID COATING AGENT TERUMO KABUSHIKI KAISHA (JP) 2019-10-17 US claimed
US-20190284200-A1 MODULATORS OF THE BETA-3 ADRENERGIC RECEPTOR USEFUL FOR THE TREATMENT OR PREVENTION OF DISORDERS RELATED THERETO ARENA PHARMACEUTICALS, INC. 2019-09-19 US claimed
WO-2004014900-A1 BENZIMIDAZOLES AND BENZOTHIAZOLES AS INHIBITORS OF MAP KINASE ELI LILLY AND COMPANY (US) 2004-02-19 WO claimed
US-20030105142-A1 Amide derivatives useful as inhibitors of the production of cytokines ASTRAZENECA AB 2003-06-05 US claimed
US-6432949-B1 Amide derivatives useful as inhibitors of the production of cytokines ASTRAZENECA AB (SE) 2002-08-13 US claimed
EP-1102743-B1 AMIDE DERIVATIVES WHICH ARE USEFUL AS CYTOKINE INHIBITORS ASTRAZENECA AB (SE) 2002-07-24 EP claimed
CN-1330631-A Amide derivatives which are useful as cell factor inhibitors ASTRA ZENECA LTD (SE) 2002-01-09 CN claimed
CN-1321150-A Amide derivs. useful as inhibitors of production of cytokines ASTRAZENECA AB (SE) 2001-11-07 CN claimed
EP-1102750-A1 AMIDE DERIVATIVES USEFUL AS INHIBITORS OF THE PRODUCTION OF CYTOKINES AstraZeneca AB (SE) 2001-05-30 EP claimed
EP-1102743-A1 AMIDE DERIVATIVES WHICH ARE USEFUL AS CYTOKINE INHIBITORS AstraZeneca AB (SE) 2001-05-30 EP claimed
WO-2000007991-A1 AMIDE DERIVATIVES USEFUL AS INHIBITORS OF THE PRODUCTION OF CYTOKINES ASTRAZENECA AB (SE) 2000-02-17 WO claimed
WO-2000007980-A1 AMIDE DERIVATIVES WHICH ARE USEFUL AS CYTOKINE INHIBITORS ASTRAZENECA AB (SE) 2000-02-17 WO claimed