Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | PLA2G4B | P0C869 | 6/20 | 0.57 |
| ▸ | RARB | P10826 | 3/20 | 0.55 |
| ▸ | HTT | P42858 | 3/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.51 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.51 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | APEX1 | P27695 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4410600 | 1.00 | TP53 (0.59) | TP53TSHRPLA2G4BRARBHTT | |
| SCHEMBL29797154 | 0.91 | TP53 (0.70) | TP53TSHRPLA2G4BRARBHTT | |
| SCHEMBL28820484 | 0.89 | TP53 (0.67) | TP53TSHRPLA2G4BRARBHTT | |
| SCHEMBL28708025 | 0.87 | TP53 (0.60) | TP53TSHRPLA2G4BRARBHTT | |
| SCHEMBL28718548 | 0.87 | TP53 (0.60) | TP53TSHRPLA2G4BRARBHTT | |
| SCHEMBL23986318 | 0.87 | TP53 (0.60) | TP53TSHRPLA2G4BRARBHTT | |
| SCHEMBL1701663 | 0.87 | TP53 (0.60) | TP53TSHRPLA2G4BRARBHTT | |
| SCHEMBL23986568 | 0.87 | TP53 (0.60) | TP53TSHRPLA2G4BRARBHTT | |
| SCHEMBL1701662 | 0.87 | TP53 (0.60) | TP53TSHRPLA2G4BRARBHTT | |
| SCHEMBL18064417 | 0.86 | HDAC3 (0.62) | HDAC3HDAC4HDAC1HDAC7HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8263192-B2 | Methods for modifying surfaces | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2012-09-11 | — | — | US | disclosed |
| US-8263192-B2 | Methods for modifying surfaces | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2012-09-11 | — | — | US | disclosed |
| US-20070134420-A1 | Methods for modifying surfaces | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2007-06-14 | — | — | US | disclosed |
| US-20070134420-A1 | Methods for modifying surfaces | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2007-06-14 | — | — | US | disclosed |
| WO-2005060668-A2 | METHODS OF MODIFYING SURFACES | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OFNEW YORK (US) | 2005-07-07 | — | — | WO | disclosed |