SCHEMBL5578210

CC(C)C[C@H](NC(=O)[C@@H](N)CCCNC(=N)N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCC(=O)O)C(=O)O

nearest known ligand 0.59

Predicted protein targets (top 5)

	gene	UniProt	supporting neighbours	confidence
▸	RAMP3	O60896	15/20	0.59

▸	CALCR	P30988	15/20	0.59

▸	NMUR2	Q9GZQ4	4/20	0.53

▸	NMUR1	Q9HB89	4/20	0.53

▸	KEAP1	Q14145	1/20	0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL5578209	1.00	RAMP3 (0.59)	RAMP3CALCRNMUR2NMUR1KEAP1
SCHEMBL5311116	0.99	RAMP3 (0.57)	RAMP3CALCRNMUR2NMUR1KEAP1
SCHEMBL5311106	0.99	RAMP3 (0.57)	RAMP3CALCRNMUR2NMUR1KEAP1
SCHEMBL5315506	0.95	RAMP3 (0.59)	RAMP3CALCRNMUR2NMUR1
SCHEMBL5315503	0.95	RAMP3 (0.59)	RAMP3CALCRNMUR2NMUR1
SCHEMBL29736175	0.94	RAMP3 (0.58)	RAMP3CALCRNMUR2NMUR1
SCHEMBL30211026	0.91	PLK1 (0.52)	RAMP3CALCRNMUR2NMUR1
SCHEMBL31031583	0.90	RAMP3 (0.58)	RAMP3CALCRNMUR2NMUR1
SCHEMBL30973992	0.90	RAMP3 (0.54)	RAMP3CALCRNMUR2NMUR1
SCHEMBL30904643	0.89	RAMP3 (0.52)	RAMP3CALCRNMUR2NMUR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-20070099246-A1	Antibodies, assays and kits to quantitate cartilage destruction	SANDY JOHN D	2007-05-03	—	—	US	claimed