Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.81 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.81 |
| ▸ | MAPT | P10636 | 5/20 | 0.81 |
| ▸ | LMNA | P02545 | 5/20 | 0.81 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.81 |
| ▸ | MITF | O75030 | 1/20 | 0.63 |
| ▸ | ALPG | P10696 | 1/20 | 0.63 |
| ▸ | POLB | P06746 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | BCHE | P06276 | 10/20 | 0.49 |
| ▸ | ACHE | P22303 | 10/20 | 0.49 |
| ▸ | GRIN1 | Q05586 | 10/20 | 0.49 |
| ▸ | GRIN2A | Q12879 | 10/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5578267 | 0.90 | KDM4E (1.00) | KDM4EALDH1A1MAPTLMNAKMT2A | |
| Hydrochloric Acid SCHEMBL5578010 | 0.85 | KDM4E (0.74) | KDM4EALDH1A1MAPTLMNAKMT2A | |
| Hydrochloric Acid SCHEMBL5578269 | 0.85 | KDM4E (0.74) | KDM4EALDH1A1MAPTLMNAKMT2A | |
| Hydrochloric Acid SCHEMBL5578419 | 0.85 | KDM4E (0.74) | KDM4EALDH1A1MAPTLMNAKMT2A | |
| Hydrochloric Acid SCHEMBL5578263 | 0.84 | KDM4E (0.73) | KDM4EALDH1A1MAPTLMNAKMT2A | |
| Hydrochloric Acid SCHEMBL5578137 | 0.82 | KDM4E (0.80) | KDM4EALDH1A1MAPTLMNAKMT2A | |
| Hydrochloric Acid SCHEMBL5578330 | 0.82 | KDM4E (0.73) | KDM4EALDH1A1MAPTLMNAKMT2A | |
| Hydrochloric Acid SCHEMBL5579198 | 0.82 | KDM4E (0.85) | KDM4EALDH1A1MAPTLMNAKMT2A | |
| Hydrochloric Acid SCHEMBL5578125 | 0.79 | KDM4E (0.79) | KDM4EALDH1A1MAPTLMNAKMT2A | |
| SCHEMBL5043373 | 0.75 | KDM4E (0.67) | KDM4EALDH1A1MAPTLMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070232538-A1 | Uses of polypeptides | TAKEDA PHARMACEUTICAL COMPANY, LTD (JP) | 2007-10-04 | — | — | US | disclosed |
| US-20040053826-A1 | Uses of polypeptides | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2004-03-18 | — | — | US | disclosed |
| EP-1308513-A1 | USE OF POLYPEPTIDE | Takeda Chemical Industries, Ltd. (JP) | 2003-05-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070232538-A1 | Uses of polypeptides | NPSR1, SCTR, GRPR | KDM4E 4438/4885ALDH1A1 3946/4885MAPT 2628/4885 |
| US-20040053826-A1 | Uses of polypeptides | NPSR1, SCTR, GRPR | KDM4E 4438/4885ALDH1A1 3946/4885MAPT 2628/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.