Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC2 | Q92769 | 5/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8239932 | 0.93 | HDAC2 (0.58) | HDAC2HDAC8HDAC6KDM4EMEN1 | |
| SCHEMBL5075674 | 0.91 | HDAC2 (0.71) | HDAC2HDAC8HDAC6KDM4EMEN1 | |
| SCHEMBL5075673 | 0.91 | HDAC2 (0.71) | HDAC2HDAC8HDAC6KDM4EMEN1 | |
| SCHEMBL5579725 | 0.91 | HDAC2 (0.54) | HDAC2HDAC8HDAC6KDM4EMEN1 | |
| SCHEMBL5137445 | 0.84 | HDAC2 (0.64) | HDAC2HDAC8HDAC6KDM4EMEN1 | |
| SCHEMBL5082209 | 0.74 | HDAC6 (0.78) | HDAC2HDAC8HDAC6 | |
| SCHEMBL5082202 | 0.74 | HDAC6 (0.78) | HDAC2HDAC8HDAC6 | |
| SCHEMBL5077641 | 0.74 | HDAC6 (1.00) | HDAC2HDAC8HDAC6 | |
| SCHEMBL5077642 | 0.74 | HDAC6 (1.00) | HDAC2HDAC8HDAC6 | |
| SCHEMBL31689330 | 0.72 | KMT2A (0.54) | KDM4EMEN1ALDH1A1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070155730-A1 | Benzodiazepine And Benzopiperazine Analog Inhibitors Of Histone Deacetylase | METHYLGENE, INC. (CA) | 2007-07-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070155730-A1 | Benzodiazepine And Benzopiperazine Analog Inhibitors Of Histone Deacetylase | HDAC5, HDAC4, HDAC3 | HDAC2 4/4885HDAC8 9/4885HDAC6 24/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.