⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19638394 | 0.96 | MEN1 (0.31) | — | |
| SCHEMBL710562 | 0.96 | MEN1 (0.31) | — | |
| SCHEMBL3471564 | 0.88 | — | — | |
| SCHEMBL3459549 | 0.87 | — | — | |
| SCHEMBL3459428 | 0.85 | — | — | |
| SCHEMBL3459015 | 0.85 | — | — | |
| SCHEMBL3459462 | 0.82 | — | — | |
| SCHEMBL9907096 | 0.82 | — | — | |
| SCHEMBL17598855 | 0.77 | — | — | |
| SCHEMBL14279972 | 0.77 | MEN1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 423 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210113668-A1 | COMPOSITION FOR INCREASING THE EXPRESSION OF A GROWTH FACTOR GENE, COMPRISING CORESHELL STRUCTURED MICROPARTICLES AS ACTIVE INGREDIENT | G&P BIOSCIENCE CO., LTD. (KR) | 2021-04-22 | — | — | US | claimed |
| US-20210113480-A1 | COMPOSITION FOR INCREASING EXPRESSION OF BLOOD COAGULATION FACTOR GENE, COMPRISING CORE-SHELL STRUCTURED MICROPARTICLES AS ACTIVE INGREDIENT | G&P BIOSCIENCE CO., LTD. (KR) | 2021-04-22 | — | — | US | claimed |
| CN-112218622-A | Composition for increasing expression of coagulation factor gene comprising core-shell structured fine particles as active ingredient | 吉恩博生物科学有限公司 | 2021-01-12 | — | — | CN | claimed |
| CN-112203644-A | Composition for increasing expression of growth factor gene comprising core-shell structured microparticle as active ingredient | 吉恩博生物科学有限公司 | 2021-01-08 | — | — | CN | claimed |
| EP-3753551-A1 | COMPOSITION FOR INCREASING EXPRESSION OF GROWTH FACTOR GENE, COMPRISING CORE-SHELL STRUCTURED MICROPARTICLES AS ACTIVE INGREDIENT | G&P Bioscience Co., Ltd. (KR) | 2020-12-23 | — | — | EP | claimed |
| EP-3753550-A1 | COMPOSITION FOR INCREASING EXPRESSION OF BLOOD COAGULATION FACTOR GENE, COMPRISING CORE-SHELL STRUCTURED MICROPARTICLES AS ACTIVE INGREDIENT | G&P Bioscience Co., Ltd. (KR) | 2020-12-23 | — | — | EP | claimed |
| WO-2019156541-A1 | COMPOSITION FOR INCREASING EXPRESSION OF BLOOD COAGULATION FACTOR GENE, COMPRISING CORE-SHELL STRUCTURED MICROPARTICLES AS ACTIVE INGREDIENT | 주식회사 지앤피바이오사이언스 | 2019-08-15 | — | — | WO | claimed |
| US-20190247525-A1 | Copper Sulfide Perfluorocarbon Nanocarriers | GEORGIA TECH RESEARCH CORPORATION | 2019-08-15 | — | — | US | claimed |
| EP-2603238-B1 | METHODS AND PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF AN OCULAR DISEASE IN A SUBJECT | INSERM INST NAT DE LA SANTÉ ET DE LA RECH MÉDICALE (FR) | 2014-07-30 | — | — | EP | claimed |
| EP-1590006-B1 | ULTRASOUND CONTRAST AGENTS AND PROCESS FOR THE PREPARATION THEREOF | BRACCO SUISSE SA (CH) | 2010-09-08 | — | — | EP | claimed |
| EP-1228770-A1 | Lyophilisable contrast agent comprising gas microbubbles | BRACCO RESEARCH S.A. (CH) | 2002-08-07 | — | — | EP | claimed |
| US-20020054854-A1 | The microbubble contains a fluorocarbon gas and a modifier gas, wherein the microbubble expands and shrinks to maintain osmotic equilibrium with physiological gas saturation of surrounding external medium | TARGESON, INC. | 2002-05-09 | — | — | US | claimed |
| US-6287539-B1 | MEDICAL DIAGNOSIS | ALLIANCE PHARMACEUTICALS CORP. | 2001-09-11 | — | — | US | claimed |
| US-6280705-B1 | MICROBUBBLE GAS OSMOTIC AGENT, SURFACTANT, AND PHOSPHATIDE; STABILITY; CONTRAST INTENSIFIERS | ALLIANCE PHARMACEUTICAL CORP. | 2001-08-28 | — | — | US | claimed |
| US-6280704-B1 | MICROBUBBLES OSMOTICALLY STABILIZED WITH PERFLUOROCARBON GAS | ALLIANCE PHARMACEUTICAL CORP. | 2001-08-28 | — | — | US | claimed |
| US-6258339-B1 | INJECTABLE ULTRASOUND CONTRAST ENHANCEMENT AGENTS OF DIFFERENT DENSITY AND HIGHER COMPRESSIBILITY THAN THE SURROUNDING FLUID | ALLIANCE PHARMACEUTICAL CORP. | 2001-07-10 | — | — | US | claimed |
| US-5798091-A | DISSOLVING A MICROSPHERES MADE OF TWO SURFACTANTS, FIRST ONE IS PHOSPHOLIPIDS AND SECOND, MORE WATER SOULBLE SURFACTANT, A HYDROPHILIC MONOMER OR POLYMER AND GAS MIXTURE TO AN AQUEOUS SOLUTION AND FORMING GAS EMULSION; ULTRASOUND IMAGING | ALLIANCE PHARMACEUTICAL CORP. (US) | 1998-08-25 | — | — | US | claimed |
| US-5720938-A | CHAMBER CONTAINING VOID-CONTAINING STRUCTURES, FLUOROCARBON GAS OSMOTIC AGENT, SECOND CHAMBER CONTAINING AQUEOUS LIQUID, SURFACTANT, SEAL SEPARATING FIRST AND SECOND CHAMBERS; ULTRASOUND CONTRAST AGENT | ALLIANCE PHARMACEUTICAL CORP. (US) | 1998-02-24 | — | — | US | claimed |
| US-5695741-A | Stable microbubble precursors | ALLIANCE PHARMACEUTICAL CORP. (US) | 1997-12-09 | — | — | US | claimed |
| US-5605673-A | SURROUNDING A FIRST AND SECOND GAS WITH A MEMBRANE FORMING MATERIAL SUCH AS A SURFACTANT | ALLIANCE PHARMACEUTICAL CORP. (US) | 1997-02-25 | — | — | US | claimed |