SCHEMBL5579724

SCHEMBL5579724

CCCCN(CCCOc1ccccc1C(=O)O)c1nc2ccccc2o1

nearest known ligand 0.52

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 19/20 0.52
PPARG P37231 16/20 0.52
PPARD Q03181 16/20 0.52
ELANE P08246 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5579706 0.97 PPARA (0.52) PPARAPPARGPPARDELANE
SCHEMBL5273658 0.96 PPARA (0.58) PPARAPPARGPPARD
SCHEMBL5274267 0.96 PPARA (0.58) PPARAPPARGPPARD
SCHEMBL5272201 0.96 PPARA (0.51) PPARAPPARGPPARD
SCHEMBL5276156 0.94 PPARG (0.58) PPARAPPARGPPARDELANE
SCHEMBL5276379 0.93 PPARG (0.57) PPARAPPARGPPARDELANE
SCHEMBL5271988 0.93 PPARG (0.57) PPARAPPARGPPARDELANE
SCHEMBL5277585 0.93 PPARA (0.52) PPARAPPARGPPARD
SCHEMBL14366175 0.91 PPARA (0.60) PPARAPPARGPPARD
SCHEMBL5274279 0.91 PPARG (0.49) PPARAPPARGPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7301033-B2 PPAR-activating compound KOWA CO., LTD. (JP) 2007-11-27 US disclosed
US-7301033-B2 PPAR-activating compound KOWA CO., LTD. (JP) 2007-11-27 US disclosed
US-7301033-B2 PPAR-activating compound KOWA CO., LTD. (JP) 2007-11-27 US disclosed
US-20060167058-A1 PPAR-activating compound KOWA CO., LTD. (JP) 2006-07-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060167058-A1 PPAR-activating compound PPARA, PPARG, PPARD PPARA 1/4885PPARG 2/4885PPARD 3/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.