Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TSPO | P30536 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 3/20 | 0.33 |
| ▸ | CTSD | P07339 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5579450 | 0.91 | KMT2A (0.45) | KMT2AALDH1A1LMNAPOLBMEN1 | |
| SCHEMBL5125015 | 0.91 | KMT2A (0.45) | KMT2AALDH1A1LMNAPOLBMEN1 | |
| SCHEMBL5126633 | 0.80 | MEN1 (0.43) | KMT2AALDH1A1LMNAPOLBBACE1 | |
| SCHEMBL5579820 | 0.76 | BACE1 (0.41) | KMT2ATSPOBACE1CTSDMEN1 | |
| SCHEMBL5579580 | 0.75 | MLLT1 (0.40) | BACE1CTSDBACE2 | |
| SCHEMBL5116447 | 0.75 | BACE1 (0.35) | TSPOBACE1CTSD | |
| SCHEMBL5131817 | 0.75 | BACE1 (0.34) | BACE1CTSD | |
| SCHEMBL5130120 | 0.74 | BACE1 (0.36) | ALDH1A1LMNATSPOBACE1CTSD | |
| SCHEMBL5126250 | 0.74 | NPC1 (0.52) | KMT2AALDH1A1LMNAMEN1SMN1; SMN2 | |
| SCHEMBL5131017 | 0.73 | BACE1 (0.39) | KMT2AALDH1A1BACE1CTSDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7294642-B2 | 1,3-Diamino-2-hydroxypropane pro-drug derivatives | ELAN PHARMACEUTICALS, INC. (US) | 2007-11-13 | — | — | US | claimed |