Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 10/20 | 0.39 |
| ▸ | CTSB | P07858 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | CTSD | P07339 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5579861 | 1.00 | KMT2A (0.40) | KMT2AKDM4EHPGDSMN1; SMN2MEN1 | |
| SCHEMBL6185848 | 1.00 | KMT2A (0.40) | KMT2AKDM4EHPGDSMN1; SMN2MEN1 | |
| SCHEMBL3353140 | 0.81 | BACE1 (0.54) | BACE1CTSBCTSD | |
| SCHEMBL3353134 | 0.81 | BACE1 (0.54) | BACE1CTSBCTSD | |
| SCHEMBL5130395 | 0.79 | BACE1 (0.43) | KMT2AMEN1BACE1CTSBCTSD | |
| SCHEMBL5130398 | 0.79 | BACE1 (0.43) | KMT2AMEN1BACE1CTSBCTSD | |
| SCHEMBL5130674 | 0.78 | SRC (0.43) | BACE1CTSBCTSD | |
| SCHEMBL5130679 | 0.78 | SRC (0.43) | BACE1CTSBCTSD | |
| SCHEMBL5130673 | 0.78 | BACE1 (0.42) | KMT2ASMN1; SMN2MEN1MAPTBACE1 | |
| SCHEMBL5130678 | 0.78 | BACE1 (0.42) | KMT2ASMN1; SMN2MEN1MAPTBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7294642-B2 | 1,3-Diamino-2-hydroxypropane pro-drug derivatives | ELAN PHARMACEUTICALS, INC. (US) | 2007-11-13 | — | — | US | claimed |