Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 20/20 | 0.53 |
| ▸ | CTSD | P07339 | 3/20 | 0.53 |
| ▸ | BACE2 | Q9Y5Z0 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14131373 | 0.89 | BACE1 (0.53) | BACE1CTSDBACE2 | |
| Hydrochloric Acid SCHEMBL5118529 | 0.89 | BACE1 (0.52) | BACE1CTSDBACE2 | |
| Hydrochloric Acid SCHEMBL5117880 | 0.89 | BACE1 (0.52) | BACE1CTSDBACE2 | |
| Hydrochloric Acid SCHEMBL5117871 | 0.89 | BACE1 (0.52) | BACE1CTSDBACE2 | |
| Hydrochloric Acid SCHEMBL5118534 | 0.89 | BACE1 (0.52) | BACE1CTSDBACE2 | |
| SCHEMBL5118530 | 0.88 | BACE1 (0.40) | BACE1CTSD | |
| SCHEMBL5118535 | 0.88 | BACE1 (0.40) | BACE1CTSD | |
| Hydrochloric Acid SCHEMBL5579555 | 0.88 | BACE1 (0.39) | BACE1CTSD | |
| Hydrochloric Acid SCHEMBL5579552 | 0.88 | BACE1 (0.39) | BACE1CTSD | |
| SCHEMBL5118512 | 0.87 | BACE1 (0.68) | BACE1CTSDBACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7294642-B2 | 1,3-Diamino-2-hydroxypropane pro-drug derivatives | ELAN PHARMACEUTICALS, INC. (US) | 2007-11-13 | — | — | US | claimed |