Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 9/20 | 0.44 |
| ▸ | WNT3A | P56704 | 9/20 | 0.44 |
| ▸ | BACE1 | P56817 | 10/20 | 0.37 |
| ▸ | CTSD | P07339 | 2/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 8/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5579887 | 1.00 | CTNNB1 (0.44) | CTNNB1WNT3ABACE1CTSDACHE | |
| SCHEMBL5579933 | 0.92 | CTNNB1 (0.41) | CTNNB1WNT3ABACE1CTSDCTSB | |
| SCHEMBL5579937 | 0.92 | CTNNB1 (0.41) | CTNNB1WNT3ABACE1CTSDCTSB | |
| SCHEMBL5579479 | 0.91 | CTNNB1 (0.44) | CTNNB1WNT3ABACE1CTSD | |
| SCHEMBL5129603 | 0.84 | BACE1 (0.41) | BACE1CTSDCTSB | |
| SCHEMBL5129607 | 0.84 | BACE1 (0.41) | BACE1CTSDCTSB | |
| SCHEMBL5124704 | 0.83 | BACE1 (0.46) | BACE1CTSDCTSB | |
| SCHEMBL5126067 | 0.83 | BACE1 (0.42) | BACE1CTSDCTSB | |
| SCHEMBL5126056 | 0.83 | BACE1 (0.42) | BACE1CTSDCTSB | |
| SCHEMBL5124714 | 0.83 | BACE1 (0.46) | BACE1CTSDCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7294642-B2 | 1,3-Diamino-2-hydroxypropane pro-drug derivatives | ELAN PHARMACEUTICALS, INC. (US) | 2007-11-13 | — | — | US | claimed |