SCHEMBL5580693

SCHEMBL5580693

CC[C@@H](Oc1nc(Oc2cc(CC(=O)NC)cc(-c3cccc(CN)c3)c2)c(F)cc1F)C(=O)O

nearest known ligand 0.78

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PLAU P00749 20/20 0.78
PLG P00747 14/20 0.78
PLAT P00750 8/20 0.78

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5580694 1.00 PLAU (0.78) PLAUPLGPLAT
SCHEMBL5581027 0.92 PLAU (0.83) PLAUPLGPLAT
SCHEMBL5581025 0.92 PLAU (0.83) PLAUPLGPLAT
SCHEMBL5581608 0.91 PLAU (0.79) PLAUPLGPLAT
SCHEMBL5581598 0.91 PLAU (0.79) PLAUPLGPLAT
SCHEMBL5581581 0.90 PLAU (0.86) PLAUPLGPLAT
SCHEMBL5581589 0.90 PLAU (0.86) PLAUPLGPLAT
SCHEMBL5580846 0.89 PLAU (0.79) PLAUPLGPLAT
SCHEMBL5580837 0.89 PLAU (0.79) PLAUPLGPLAT
SCHEMBL5581167 0.89 PLAU (0.88) PLAUPLGPLAT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070148164-A1 Neonatal Fc receptor (FcRn)-binding polypeptide variants, dimeric Fc binding proteins and methods related thereto BIOGEN IDEC MA INC. (US) 2007-06-28 US disclosed