SCHEMBL5580907

SCHEMBL5580907

Cc1cc(Oc2cccc(-c3ccc(C)cc3C(=O)O)n2)cc(-c2cccc(CN)c2)c1

nearest known ligand 0.54

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PLAU P00749 19/20 0.54
PLG P00747 14/20 0.54
PLAT P00750 7/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5581915 0.92 PLAU (0.48) PLAUPLGPLAT
Hydrochloric Acid SCHEMBL5581245 0.92 PLAU (0.56) PLAUPLGPLAT
SCHEMBL5580874 0.92 PLAU (0.51) PLAUPLGPLAT
Hydrochloric Acid SCHEMBL5580981 0.91 PLAU (0.48) PLAUPLGPLAT
SCHEMBL5581397 0.91 PLAU (0.47) PLAUPLGPLAT
Hydrochloric Acid SCHEMBL5581462 0.91 PLAU (0.51) PLAUPLGPLAT
Hydrochloric Acid SCHEMBL5581039 0.90 PLAU (0.49) PLAUPLGPLAT
SCHEMBL5581170 0.90 PLAU (0.46) PLAUPLGPLAT
Hydrochloric Acid SCHEMBL5580802 0.90 PLAU (0.51) PLAUPLGPLAT
Hydrochloric Acid SCHEMBL5581003 0.90 PLAU (0.47) PLAUPLGPLAT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070148164-A1 Neonatal Fc receptor (FcRn)-binding polypeptide variants, dimeric Fc binding proteins and methods related thereto BIOGEN IDEC MA INC. (US) 2007-06-28 US disclosed