SCHEMBL5580968

SCHEMBL5580968

Cc1ccc(C(=O)O)c(Oc2nc(Oc3cc(-c4cccc(CN)c4)ccc3C)c(F)cc2F)c1

nearest known ligand 0.84

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PLAU P00749 20/20 0.84
PLG P00747 14/20 0.84
PLAT P00750 6/20 0.84

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5581860 0.96 PLAU (0.91) PLAUPLGPLAT
SCHEMBL5581685 0.92 PLAU (1.00) PLAUPLGPLAT
SCHEMBL5580713 0.90 PLAU (0.80) PLAUPLGPLAT
SCHEMBL5581624 0.90 PLAU (0.80) PLAUPLGPLAT
SCHEMBL5581735 0.90 PLAU (1.00) PLAUPLGPLAT
SCHEMBL5580780 0.88 PLAU (1.00) PLAUPLGPLAT
SCHEMBL5581312 0.88 PLAU (0.77) PLAUPLGPLAT
SCHEMBL5581436 0.87 PLAU (0.91) PLAUPLGPLAT
SCHEMBL5581340 0.86 PLAU (0.74) PLAUPLGPLAT
SCHEMBL5581956 0.85 PLAU (1.00) PLAUPLGPLAT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070148164-A1 Neonatal Fc receptor (FcRn)-binding polypeptide variants, dimeric Fc binding proteins and methods related thereto BIOGEN IDEC MA INC. (US) 2007-06-28 US disclosed