SCHEMBL5580988

SCHEMBL5580988

NCc1cccc(-c2cccc(Oc3nc(OCC(=O)O)c(F)cc3F)c2)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PLAU P00749 20/20 1.00
PLG P00747 13/20 0.71
PLAT P00750 7/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5580889 0.87 PLAU (1.00) PLAUPLGPLAT
SCHEMBL5580810 0.86 PLAU (0.74) PLAUPLGPLAT
SCHEMBL5581485 0.84 PLAU (0.72) PLAUPLGPLAT
SCHEMBL5581850 0.83 PLAU (0.71) PLAUPLGPLAT
SCHEMBL5581502 0.83 PLAU (1.00) PLAUPLGPLAT
SCHEMBL5580814 0.83 PLAU (0.71) PLAUPLGPLAT
SCHEMBL5581131 0.83 PLAU (1.00) PLAUPLGPLAT
SCHEMBL5581123 0.83 PLAU (1.00) PLAUPLGPLAT
SCHEMBL5581432 0.83 PLAU (1.00) PLAUPLGPLAT
SCHEMBL5580863 0.82 PLAU (0.84) PLAUPLGPLAT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070148164-A1 Neonatal Fc receptor (FcRn)-binding polypeptide variants, dimeric Fc binding proteins and methods related thereto BIOGEN IDEC MA INC. (US) 2007-06-28 US disclosed