SCHEMBL5581001

SCHEMBL5581001

CNc1c(F)c(Oc2cccc(-c3cccc(CN)c3)c2)nc(Oc2cc(C)ccc2C(=O)O)c1F

nearest known ligand 0.80

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PLAU P00749 20/20 0.80
PLG P00747 17/20 0.80
PLAT P00750 10/20 0.80

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5581165 0.91 PLAU (0.84) PLAUPLGPLAT
SCHEMBL5581510 0.91 PLAU (0.75) PLAUPLGPLAT
SCHEMBL5581300 0.90 PLAU (0.83) PLAUPLGPLAT
SCHEMBL5581644 0.90 PLAU (0.83) PLAUPLGPLAT
SCHEMBL5581257 0.90 PLAU (0.83) PLAUPLGPLAT
SCHEMBL5581419 0.89 PLAU (1.00) PLAUPLGPLAT
SCHEMBL5580790 0.89 PLAU (0.77) PLAUPLGPLAT
SCHEMBL5581735 0.88 PLAU (1.00) PLAUPLGPLAT
SCHEMBL5580816 0.88 PLAU (0.71) PLAUPLGPLAT
SCHEMBL5580826 0.86 PLAU (0.74) PLAUPLGPLAT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070148164-A1 Neonatal Fc receptor (FcRn)-binding polypeptide variants, dimeric Fc binding proteins and methods related thereto BIOGEN IDEC MA INC. (US) 2007-06-28 US disclosed