SCHEMBL5581082

SCHEMBL5581082

Cc1ccc(C(=O)O)c(Oc2nc(Oc3cc(O)cc(-c4cccc(CN)c4)c3)c(F)cc2F)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PLAU P00749 20/20 1.00
PLG P00747 14/20 1.00
PLAT P00750 8/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5580780 0.94 PLAU (1.00) PLAUPLGPLAT
SCHEMBL5581436 0.93 PLAU (0.91) PLAUPLGPLAT
SCHEMBL5581735 0.92 PLAU (1.00) PLAUPLGPLAT
SCHEMBL5580741 0.91 PLAU (0.88) PLAUPLGPLAT
SCHEMBL5580884 0.91 PLAU (0.88) PLAUPLGPLAT
SCHEMBL5581956 0.91 PLAU (1.00) PLAUPLGPLAT
SCHEMBL5581860 0.89 PLAU (0.91) PLAUPLGPLAT
SCHEMBL5580746 0.89 PLAU (0.84) PLAUPLGPLAT
SCHEMBL5581384 0.89 PLAU (0.84) PLAUPLGPLAT
SCHEMBL5581349 0.89 PLAU (0.84) PLAUPLGPLAT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070148164-A1 Neonatal Fc receptor (FcRn)-binding polypeptide variants, dimeric Fc binding proteins and methods related thereto BIOGEN IDEC MA INC. (US) 2007-06-28 US disclosed