SCHEMBL5581185

SCHEMBL5581185

CCC[C@@H](Oc1nc(Oc2cc(OC)cc(-c3cccc(CN)c3)c2)c(F)cc1F)C(=O)O

nearest known ligand 0.74

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PLAU P00749 20/20 0.74
PLG P00747 14/20 0.74
PLAT P00750 8/20 0.74

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5581188 1.00 PLAU (0.74) PLAUPLGPLAT
SCHEMBL5581420 0.95 PLAU (0.72) PLAUPLGPLAT
SCHEMBL5581426 0.95 PLAU (0.72) PLAUPLGPLAT
SCHEMBL5581523 0.93 PLAU (0.84) PLAUPLGPLAT
SCHEMBL5581534 0.93 PLAU (0.84) PLAUPLGPLAT
SCHEMBL5581808 0.92 PLAU (0.86) PLAUPLGPLAT
SCHEMBL5581968 0.91 PLAU (0.87) PLAUPLGPLAT
SCHEMBL5581979 0.91 PLAU (0.87) PLAUPLGPLAT
SCHEMBL5580956 0.91 PLAU (0.72) PLAUPLGPLAT
SCHEMBL5580950 0.91 PLAU (0.72) PLAUPLGPLAT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070148164-A1 Neonatal Fc receptor (FcRn)-binding polypeptide variants, dimeric Fc binding proteins and methods related thereto BIOGEN IDEC MA INC. (US) 2007-06-28 US disclosed