SCHEMBL5581592

SCHEMBL5581592

Cc1c(F)c(NCCC(=O)O)nc(Oc2cccc(-c3cccc(C(=N)N)c3)c2)c1F

nearest known ligand 0.61

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
F10 P00742 18/20 0.61
F2 P00734 3/20 0.59
PLG P00747 1/20 0.58
PLAU P00749 1/20 0.58
PLAT P00750 1/20 0.58
F7 P08709 1/20 0.55
F3 P13726 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5580879 0.82 F10 (0.89) F10F2PLGPLAUPLAT
SCHEMBL5581381 0.81 F10 (0.77) F10F2PLGPLAUPLAT
SCHEMBL6578684 0.81 F10 (0.73) F10F2F7F3
SCHEMBL6581188 0.78 F10 (0.70) F10F2
SCHEMBL5580850 0.78 F7 (0.89) F10F2PLGPLAUPLAT
SCHEMBL5581205 0.78 F10 (0.87) F10F2PLGPLAUPLAT
SCHEMBL6578965 0.78 F10 (0.87) F10F2
SCHEMBL6576440 0.76 F10 (1.00) F10F2F7F3
SCHEMBL6578913 0.76 F10 (1.00) F10F2
SCHEMBL5581324 0.76 F3 (0.72) F10F2PLGPLAUPLAT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070148164-A1 Neonatal Fc receptor (FcRn)-binding polypeptide variants, dimeric Fc binding proteins and methods related thereto BIOGEN IDEC MA INC. (US) 2007-06-28 US disclosed