SCHEMBL5581658

SCHEMBL5581658

Cc1ccc(C(=O)O)c(Oc2nc(Oc3cccc(-c4cccc(CN)c4)c3)c(F)c(N3CCC(C(=O)NCCc4c[nH]cn4)C3)c2F)c1

nearest known ligand 0.59

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PLAU P00749 20/20 0.59
PLG P00747 17/20 0.59
PLAT P00750 10/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5581255 0.86 PLAU (0.69) PLAUPLGPLAT
SCHEMBL5580892 0.85 PLAU (0.62) PLAUPLGPLAT
SCHEMBL5581761 0.85 PLAU (0.72) PLAUPLGPLAT
SCHEMBL5581650 0.85 PLAU (0.62) PLAUPLGPLAT
SCHEMBL5581353 0.84 PLAU (0.64) PLAUPLGPLAT
SCHEMBL5581923 0.84 PLAU (0.69) PLAUPLGPLAT
SCHEMBL5581169 0.84 PLAU (0.64) PLAUPLGPLAT
SCHEMBL5581321 0.83 PLAU (0.65) PLAUPLGPLAT
SCHEMBL5581261 0.83 PLAU (0.63) PLAUPLGPLAT
SCHEMBL5581437 0.83 PLAU (0.60) PLAUPLGPLAT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070148164-A1 Neonatal Fc receptor (FcRn)-binding polypeptide variants, dimeric Fc binding proteins and methods related thereto BIOGEN IDEC MA INC. (US) 2007-06-28 US disclosed