Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 19/20 | 0.82 |
| ▸ | PLG | P00747 | 14/20 | 0.82 |
| ▸ | PLAT | P00750 | 7/20 | 0.69 |
| ▸ | F7 | P08709 | 1/20 | 0.65 |
| ▸ | F3 | P13726 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5582017 | 0.92 | PLAU (0.72) | PLAUPLGPLAT | |
| SCHEMBL5581165 | 0.90 | PLAU (0.84) | PLAUPLGPLAT | |
| SCHEMBL5581432 | 0.90 | PLAU (1.00) | PLAUPLGPLAT | |
| SCHEMBL5581363 | 0.90 | PLAU (0.69) | PLAUPLGPLATF7F3 | |
| SCHEMBL5581876 | 0.89 | PLAU (0.70) | PLAUPLGPLAT | |
| SCHEMBL5581424 | 0.89 | PLAU (0.70) | PLAUPLGPLAT | |
| SCHEMBL5581753 | 0.89 | PLAU (0.83) | PLAUPLGPLAT | |
| SCHEMBL5581438 | 0.88 | PLAU (0.71) | PLAUPLGPLAT | |
| SCHEMBL5581387 | 0.87 | PLAU (0.69) | PLAUPLGPLAT | |
| SCHEMBL5581518 | 0.87 | PLAU (0.87) | PLAUPLGPLATF7F3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070148164-A1 | Neonatal Fc receptor (FcRn)-binding polypeptide variants, dimeric Fc binding proteins and methods related thereto | BIOGEN IDEC MA INC. (US) | 2007-06-28 | — | — | US | disclosed |